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Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.
Stappers MHT, Clark AE, Aimanianda V, Bidula S, Reid DM, Asamaphan P, Hardison SE, Dambuza IM, Valsecchi I, Kerscher B, Plato A, Wallace CA, Yuecel R, Hebecker B, da Glória Teixeira Sousa M, Cunha C, Liu Y, Feizi T, Brakhage AA, Kwon-Chung KJ, Gow NAR, Zanda M, Piras M, Zanato C, Jaeger M, Netea MG, van de Veerdonk FL, Lacerda JF, Campos A, Carvalho A, Willment JA, Latgé JP, Brown GD. Stappers MHT, et al. Nature. 2018 Mar 15;555(7696):382-386. doi: 10.1038/nature25974. Epub 2018 Feb 28. Nature. 2018. PMID: 29489751 Free PMC article.
Aspergillus fumigatus conidial melanin modulates host cytokine response.
Chai LY, Netea MG, Sugui J, Vonk AG, van de Sande WW, Warris A, Kwon-Chung KJ, Kullberg BJ. Chai LY, et al. Immunobiology. 2010 Nov;215(11):915-20. doi: 10.1016/j.imbio.2009.10.002. Epub 2009 Nov 25. Immunobiology. 2010. PMID: 19939494 Free PMC article.
Aspergillus fumigatus and related species.
Sugui JA, Kwon-Chung KJ, Juvvadi PR, Latgé JP, Steinbach WJ. Sugui JA, et al. Cold Spring Harb Perspect Med. 2014 Nov 6;5(2):a019786. doi: 10.1101/cshperspect.a019786. Cold Spring Harb Perspect Med. 2014. PMID: 25377144 Free PMC article. Review.
Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis.
Kyrmizi I, Ferreira H, Carvalho A, Figueroa JAL, Zarmpas P, Cunha C, Akoumianaki T, Stylianou K, Deepe GS Jr, Samonis G, Lacerda JF, Campos A Jr, Kontoyiannis DP, Mihalopoulos N, Kwon-Chung KJ, El-Benna J, Valsecchi I, Beauvais A, Brakhage AA, Neves NM, Latge JP, Chamilos G. Kyrmizi I, et al. Nat Microbiol. 2018 Jul;3(7):791-803. doi: 10.1038/s41564-018-0167-x. Epub 2018 May 30. Nat Microbiol. 2018. PMID: 29849062
293 results