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STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy.
Wang-Bishop L, Kimmel BR, Ngwa VM, Madden MZ, Baljon JJ, Florian DC, Hanna A, Pastora LE, Sheehy TL, Kwiatkowski AJ, Wehbe M, Wen X, Becker KW, Garland KM, Schulman JA, Shae D, Edwards D, Wolf MM, Delapp R, Christov PP, Beckermann KE, Balko JM, Rathmell WK, Rathmell JC, Chen J, Wilson JT. Wang-Bishop L, et al. Among authors: kwiatkowski aj. Sci Immunol. 2023 May 12;8(83):eadd1153. doi: 10.1126/sciimmunol.add1153. Epub 2023 May 5. Sci Immunol. 2023. PMID: 37146128
Nanoparticle Delivery of Immunostimulatory Alu RNA for Cancer Immunotherapy.
Garland KM, Kwiatkowski AJ, Tossberg JT, Crooke PS 3rd, Aune TM, Wilson JT. Garland KM, et al. Among authors: kwiatkowski aj. Cancer Res Commun. 2023 Sep 8;3(9):1800-1809. doi: 10.1158/2767-9764.CRC-22-0354. eCollection 2023 Sep. Cancer Res Commun. 2023. PMID: 37691856 Free PMC article.
STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy.
Sheehy TL, Kwiatkowski AJ, Arora K, Kimmel BR, Schulman JA, Gibson-Corley K, Wilson JT. Sheehy TL, et al. Among authors: kwiatkowski aj. bioRxiv [Preprint]. 2024 Apr 12:2024.03.23.585817. doi: 10.1101/2024.03.23.585817. bioRxiv. 2024. PMID: 38585879 Free PMC article. Preprint.
Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.
Palmer CR, Pastora LE, Kimmel BR, Pagendarm HM, Kwiatkowski AJ, Stone PT, Arora K, Francini N, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: kwiatkowski aj. Adv Healthc Mater. 2024 Apr 22:e2303815. doi: 10.1002/adhm.202303815. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38648653
Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+ T cells.
Helm EY, Zelenka T, Cismasiu VB, Islam S, Silvane L, Zitti B, Holmes TD, Drashansky TT, Kwiatkowski AJ, Tao C, Dean J, Obermayer AN, Chen X, Keselowsky BG, Zhang W, Huo Z, Zhou L, Sheridan BS, Conejo-Garcia JR, Shaw TI, Bryceson YT, Avram D. Helm EY, et al. Among authors: kwiatkowski aj. Sci Immunol. 2023 Apr 28;8(82):eabn0484. doi: 10.1126/sciimmunol.abn0484. Epub 2023 Apr 28. Sci Immunol. 2023. PMID: 37115913 Free PMC article.
Suppression of local inflammation via galectin-anchored indoleamine 2,3-dioxygenase.
Bracho-Sanchez E, Rocha FG, Bedingfield SK, Partain BD, Macias SL, Brusko MA, Colazo JM, Fettis MM, Farhadi SA, Helm EY, Koenders K, Kwiatkowski AJ, Restuccia A, Morales BS, Wanchoo A, Avram D, Allen KD, Duvall CL, Wallet SM, Hudalla GA, Keselowsky BG. Bracho-Sanchez E, et al. Among authors: kwiatkowski aj. Nat Biomed Eng. 2023 Sep;7(9):1156-1169. doi: 10.1038/s41551-023-01025-1. Epub 2023 May 1. Nat Biomed Eng. 2023. PMID: 37127708 Free PMC article.
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