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172 results

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ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma.
Mensali N, Köksal H, Joaquina S, Wernhoff P, Casey NP, Romecin P, Panisello C, Rodriguez R, Vimeux L, Juzeniene A, Myhre MR, Fåne A, Ramírez CC, Maggadottir SM, Duru AD, Georgoudaki AM, Grad I, Maturana AD, Gaudernack G, Kvalheim G, Carcaboso AM, de Alava E, Donnadieu E, Bruland ØS, Menendez P, Inderberg EM, Wälchli S. Mensali N, et al. Among authors: kvalheim g. Nat Commun. 2023 Jun 8;14(1):3375. doi: 10.1038/s41467-023-39097-x. Nat Commun. 2023. PMID: 37291203 Free PMC article.
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy.
Fløisand Y, Remberger M, Bigalke I, Josefsen D, Vålerhaugen H, Inderberg EM, Olaussen RW, Gjertsen BT, Goedkoop R, Geiger C, Prinz PU, Schnorfeil FM, Pinkernell K, Schendel DJ, Kvalheim G. Fløisand Y, et al. Among authors: kvalheim g. Leukemia. 2023 Sep;37(9):1842-1849. doi: 10.1038/s41375-023-01980-3. Epub 2023 Jul 28. Leukemia. 2023. PMID: 37507426
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer.
Maggadottir SM, Dueland S, Mensali N, Hamre H, Andresen PA, Myhre MR, Juul HV, Bigalke I, Lundby M, Hønnåshagen TK, Sæbøe-Larssen S, Josefsen D, Hagtvedt T, Wälchli S, Kvalheim G, Inderberg EM. Maggadottir SM, et al. Among authors: kvalheim g. Mol Ther. 2024 Apr 6:S1525-0016(24)00225-9. doi: 10.1016/j.ymthe.2024.04.009. Online ahead of print. Mol Ther. 2024. PMID: 38582964 Free article.
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16.
Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S. Casey NP, et al. Among authors: kvalheim g. J Immunother Cancer. 2024 Apr 11;12(4):e008179. doi: 10.1136/jitc-2023-008179. J Immunother Cancer. 2024. PMID: 38604812 Free PMC article.
A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer.
Thomsen LCV, Honoré A, Reisæter LAR, Almås B, Børretzen A, Helle SI, Førde K, Kristoffersen EK, Kaada SH, Melve GK, Haslerud TM, Biermann M, Bigalke I, Kvalheim G, Azeem W, Olsen JR, Gabriel B, Knappskog S, Halvorsen OJ, Akslen LA, Bahn D, Pantel K, Riethdorf S, Ragde H, Gjertsen BT, Øyan AM, Kalland KH, Beisland C. Thomsen LCV, et al. Among authors: kvalheim g. Cancer Immunol Immunother. 2023 Jul;72(7):2357-2373. doi: 10.1007/s00262-023-03421-7. Epub 2023 Mar 20. Cancer Immunol Immunother. 2023. PMID: 36939854 Free PMC article. Clinical Trial.
Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival - the FOCUS Consortium.
Gigic B, van Roekel E, Holowatyj AN, Brezina S, Geijsen AJMR, Ulvik A, Ose J, Koole JL, Damerell V, Kiblawi R, Gumpenberger T, Lin T, Kvalheim G, Koelsch T, Kok DE, van Duijnhoven FJ, Bours MJ, Baierl A, Li CI, Grady W, Vickers K, Habermann N, Schneider M, Kampman E, Ueland PM, Ulrich A, Weijenberg M, Gsur A, Ulrich C; FOCUS Consortium. Gigic B, et al. Among authors: kvalheim g. BMJ Open. 2022 Dec 22;12(12):e062930. doi: 10.1136/bmjopen-2022-062930. BMJ Open. 2022. PMID: 36549742 Free PMC article.
A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT).
Maggadóttir SM, Kvalheim G, Wernhoff P, Sæbøe-Larssen S, Revheim ME, Josefsen D, Wälchli S, Helland Å, Inderberg EM. Maggadóttir SM, et al. Among authors: kvalheim g. Front Oncol. 2022 Nov 10;12:1031232. doi: 10.3389/fonc.2022.1031232. eCollection 2022. Front Oncol. 2022. PMID: 36439452 Free PMC article.
Higher vitamin B6 status is associated with improved survival among patients with stage I-III colorectal cancer.
Holowatyj AN, Ose J, Gigic B, Lin T, Ulvik A, Geijsen AJMR, Brezina S, Kiblawi R, van Roekel EH, Baierl A, Böhm J, Bours MJL, Brenner H, Breukink SO, Chang-Claude J, de Wilt JHW, Grady WM, Grünberger T, Gumpenberger T, Herpel E, Hoffmeister M, Keulen ETP, Kok DE, Koole JL, Kosma K, Kouwenhoven EA, Kvalheim G, Li CI, Schirmacher P, Schrotz-King P, Singer MC, van Duijnhoven FJB, van Halteren HK, Vickers K, Vogelaar FJ, Warby CA, Wesselink E, Ueland PM, Ulrich AB, Schneider M, Habermann N, Kampman E, Weijenberg MP, Gsur A, Ulrich CM. Holowatyj AN, et al. Among authors: kvalheim g. Am J Clin Nutr. 2022 Aug 4;116(2):303-313. doi: 10.1093/ajcn/nqac090. Am J Clin Nutr. 2022. PMID: 35394006 Free PMC article.
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy.
Tryggestad AMA, Axcrona K, Axcrona U, Bigalke I, Brennhovd B, Inderberg EM, Hønnåshagen TK, Skoge LJ, Solum G, Saebøe-Larssen S, Josefsen D, Olaussen RW, Aamdal S, Skotheim RI, Myklebust TÅ, Schendel DJ, Lilleby W, Dueland S, Kvalheim G. Tryggestad AMA, et al. Among authors: kvalheim g. Prostate. 2022 Feb;82(2):245-253. doi: 10.1002/pros.24267. Epub 2021 Nov 11. Prostate. 2022. PMID: 34762317 Clinical Trial.
172 results