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MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".
Das SK, Kuzin V, Cameron DP, Sanford S, Jha RK, Nie Z, Rosello MT, Holewinski R, Andresson T, Wisniewski J, Natsume T, Price DH, Lewis BA, Kouzine F, Levens D, Baranello L. Das SK, et al. Among authors: kuzin v. Mol Cell. 2022 Jan 6;82(1):140-158.e12. doi: 10.1016/j.molcel.2021.11.016. Epub 2021 Dec 9. Mol Cell. 2022. PMID: 34890565 Free PMC article.
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1.
Silva Cascales H, Burdova K, Middleton A, Kuzin V, Müllers E, Stoy H, Baranello L, Macurek L, Lindqvist A. Silva Cascales H, et al. Among authors: kuzin v. Life Sci Alliance. 2021 Jan 5;4(3):e202000980. doi: 10.26508/lsa.202000980. Print 2021 Mar. Life Sci Alliance. 2021. PMID: 33402344 Free PMC article.
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1.
Wiegard A, Kuzin V, Cameron DP, Grosser J, Ceribelli M, Mehmood R, Ballarino R, Valant F, Grochowski R, Karabogdan I, Crosetto N, Lindqvist A, Bizard AH, Kouzine F, Natsume T, Baranello L. Wiegard A, et al. Among authors: kuzin v. Mol Cell. 2021 Dec 16;81(24):5007-5024.e9. doi: 10.1016/j.molcel.2021.10.015. Epub 2021 Nov 11. Mol Cell. 2021. PMID: 34767771 Free article.
Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription.
Cameron DP, Grosser J, Ladigan S, Kuzin V, Iliopoulou E, Wiegard A, Benredjem H, Jackson K, Liffers ST, Lueong S, Cheung PF, Vangala D, Pohl M, Viebahn R, Teschendorf C, Wolters H, Usta S, Geng K, Kutter C, Arsenian-Henriksson M, Siveke JT, Tannapfel A, Schmiegel W, Hahn SA, Baranello L. Cameron DP, et al. Among authors: kuzin v. Sci Adv. 2023 Oct 13;9(41):eadg5109. doi: 10.1126/sciadv.adg5109. Epub 2023 Oct 13. Sci Adv. 2023. PMID: 37831776 Free PMC article.
75 results