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PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Adhikari B, et al. Among authors: kuster b. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28. Nat Chem Biol. 2020. PMID: 32989298 Free PMC article.
ML3 is a NEDD8- and ubiquitin-modified protein.
Hakenjos JP, Bejai S, Ranftl Q, Behringer C, Vlot AC, Absmanner B, Hammes U, Heinzlmeir S, Kuster B, Schwechheimer C. Hakenjos JP, et al. Among authors: kuster b. Plant Physiol. 2013 Sep;163(1):135-49. doi: 10.1104/pp.113.221341. Epub 2013 Jul 31. Plant Physiol. 2013. PMID: 23903439 Free PMC article.
Probing SH2-domains using Inhibitor Affinity Purification (IAP).
Höfener M, Heinzlmeir S, Kuster B, Sewald N. Höfener M, et al. Among authors: kuster b. Proteome Sci. 2014 Jul 16;12:41. doi: 10.1186/1477-5956-12-41. eCollection 2014. Proteome Sci. 2014. PMID: 25067910 Free PMC article.
Optimized chemical proteomics assay for kinase inhibitor profiling.
Médard G, Pachl F, Ruprecht B, Klaeger S, Heinzlmeir S, Helm D, Qiao H, Ku X, Wilhelm M, Kuehne T, Wu Z, Dittmann A, Hopf C, Kramer K, Kuster B. Médard G, et al. Among authors: kuster b. J Proteome Res. 2015 Mar 6;14(3):1574-86. doi: 10.1021/pr5012608. Epub 2015 Feb 20. J Proteome Res. 2015. PMID: 25660469
Evaluation of Kinase Activity Profiling Using Chemical Proteomics.
Ruprecht B, Zecha J, Heinzlmeir S, Médard G, Lemeer S, Kuster B. Ruprecht B, et al. Among authors: kuster b. ACS Chem Biol. 2015 Dec 18;10(12):2743-52. doi: 10.1021/acschembio.5b00616. Epub 2015 Oct 5. ACS Chem Biol. 2015. PMID: 26378887
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: kuster b. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403
314 results