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Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Harjes S, Kurup HM, Rieffer AE, Bayarjargal M, Filitcheva J, Su Y, Hale TK, Filichev VV, Harjes E, Harris RS, Jameson GB. Harjes S, et al. Among authors: kurup hm. Nat Commun. 2023 Oct 11;14(1):6382. doi: 10.1038/s41467-023-42174-w. Nat Commun. 2023. PMID: 37821454 Free PMC article.
Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Harjes S, Kurup HM, Rieffer AE, Bayaijargal M, Filitcheva J, Su Y, Hale TK, Filichev VV, Harjes E, Harris RS, Jameson GB. Harjes S, et al. Among authors: kurup hm. bioRxiv [Preprint]. 2023 Feb 17:2023.02.17.528918. doi: 10.1101/2023.02.17.528918. bioRxiv. 2023. PMID: 36824964 Free PMC article. Updated. Preprint.
Uncoupling Molecular Testing for SARS-CoV-2 From International Supply Chains.
Stanton JL, O'Brien R, Hall RJ, Chernyavtseva A, Ha HJ, Jelley L, Mace PD, Klenov A, Treece JM, Fraser JD, Clow F, Clarke L, Su Y, Kurup HM, Filichev VV, Rolleston W, Law L, Rendle PM, Harris LD, Wood JM, Scully TW, Ussher JE, Grant J, Hore TA, Moser TV, Harfoot R, Lawley B, Quiñones-Mateu ME, Collins P, Blaikie R. Stanton JL, et al. Among authors: kurup hm. Front Public Health. 2022 Jan 24;9:808751. doi: 10.3389/fpubh.2021.808751. eCollection 2021. Front Public Health. 2022. PMID: 35141190 Free PMC article. Review.
Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.
Kvach MV, Barzak FM, Harjes S, Schares HAM, Kurup HM, Jones KF, Sutton L, Donahue J, D'Aquila RT, Jameson GB, Harki DA, Krause KL, Harjes E, Filichev VV. Kvach MV, et al. Among authors: kurup hm. Chembiochem. 2020 Apr 1;21(7):1028-1035. doi: 10.1002/cbic.201900505. Epub 2019 Dec 19. Chembiochem. 2020. PMID: 31633265 Free PMC article.