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Evaluation of cell-free DNA approaches for multi-cancer early detection.
Cancer Cell. 2022 Dec 12;40(12):1537-1549.e12. doi: 10.1016/j.ccell.2022.10.022. Epub 2022 Nov 17.
Cancer Cell. 2022.
PMID: 36400018
Free article.
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.
Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV; CCGA Consortium.
Liu MC, et al.
Ann Oncol. 2020 Jun;31(6):745-759. doi: 10.1016/j.annonc.2020.02.011. Epub 2020 Mar 30.
Ann Oncol. 2020.
PMID: 33506766
Free PMC article.
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Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA.
Chen X, Dong Z, Hubbell E, Kurtzman KN, Oxnard GR, Venn O, Melton C, Clarke CA, Shaknovich R, Ma T, Meixiong G, Seiden MV, Klein EA, Fung ET, Liu MC.
Chen X, et al. Among authors: kurtzman kn.
Clin Cancer Res. 2021 Aug 1;27(15):4221-4229. doi: 10.1158/1078-0432.CCR-21-0417. Epub 2021 Jun 4.
Clin Cancer Res. 2021.
PMID: 34088722
Free PMC article.
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Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.
Klein EA, Richards D, Cohn A, Tummala M, Lapham R, Cosgrove D, Chung G, Clement J, Gao J, Hunkapiller N, Jamshidi A, Kurtzman KN, Seiden MV, Swanton C, Liu MC.
Klein EA, et al. Among authors: kurtzman kn.
Ann Oncol. 2021 Sep;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806. Epub 2021 Jun 24.
Ann Oncol. 2021.
PMID: 34176681
Free article.
Item in Clipboard
Performance of a targeted methylation-based multi-cancer early detection test by race and ethnicity.
Tang WHW, Yimer H, Tummala M, Shao S, Chung G, Clement J, Chu BC, Hubbell E, Kurtzman KN, Swanton C, Roberts LR.
Tang WHW, et al. Among authors: kurtzman kn.
Prev Med. 2023 Feb;167:107384. doi: 10.1016/j.ypmed.2022.107384. Epub 2022 Dec 7.
Prev Med. 2023.
PMID: 36495927
Free article.
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Performance of a Cell-Free DNA-Based Multi-cancer Detection Test in Individuals Presenting With Symptoms Suspicious for Cancers.
Bryce AH, Thiel DD, Seiden MV, Richards D, Luan Y, Coignet M, Zhang Q, Zhang N, Hubbell E, Kurtzman KN, Klein EA.
Bryce AH, et al. Among authors: kurtzman kn.
JCO Precis Oncol. 2023 Jul;7:e2200679. doi: 10.1200/PO.22.00679.
JCO Precis Oncol. 2023.
PMID: 37467458
Free PMC article.
Clinical Trial.
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Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study.
Nicholson BD, Oke J, Virdee PS, Harris DA, O'Doherty C, Park JE, Hamady Z, Sehgal V, Millar A, Medley L, Tonner S, Vargova M, Engonidou L, Riahi K, Luan Y, Hiom S, Kumar H, Nandani H, Kurtzman KN, Yu LM, Freestone C, Pearson S, Hobbs FR, Perera R, Middleton MR.
Nicholson BD, et al. Among authors: kurtzman kn.
Lancet Oncol. 2023 Jul;24(7):733-743. doi: 10.1016/S1470-2045(23)00277-2. Epub 2023 Jun 20.
Lancet Oncol. 2023.
PMID: 37352875
Free article.
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