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CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.
Ligons DL, Tuncer C, Linowes BA, Akcay IM, Kurtulus S, Deniz E, Atasever Arslan B, Cevik SI, Keller HR, Luckey MA, Feigenbaum L, Möröy T, Ersahin T, Atalay R, Erman B, Park JH. Ligons DL, et al. Among authors: kurtulus s. J Biol Chem. 2012 Oct 5;287(41):34386-99. doi: 10.1074/jbc.M112.378687. Epub 2012 Aug 3. J Biol Chem. 2012. PMID: 22865857 Free PMC article.
Induction and transcriptional regulation of the co-inhibitory gene module in T cells.
Chihara N, Madi A, Kondo T, Zhang H, Acharya N, Singer M, Nyman J, Marjanovic ND, Kowalczyk MS, Wang C, Kurtulus S, Law T, Etminan Y, Nevin J, Buckley CD, Burkett PR, Buenrostro JD, Rozenblatt-Rosen O, Anderson AC, Regev A, Kuchroo VK. Chihara N, et al. Among authors: kurtulus s. Nature. 2018 Jun;558(7710):454-459. doi: 10.1038/s41586-018-0206-z. Epub 2018 Jun 13. Nature. 2018. PMID: 29899446 Free PMC article.
Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors.
Conlon K, Watson DC, Waldmann TA, Valentin A, Bergamaschi C, Felber BK, Peer CJ, Figg WD, Potter EL, Roederer M, McNeel DG, Thompson JA, Gupta S, Leidner R, Wang-Gillam A, Parikh NS, Long D, Kurtulus S, Ho Lee L, Chowdhury NR, Bender F, Pavlakis GN. Conlon K, et al. Among authors: kurtulus s. J Immunother Cancer. 2021 Nov;9(11):e003388. doi: 10.1136/jitc-2021-003388. J Immunother Cancer. 2021. PMID: 34799399 Free PMC article. Clinical Trial.
STAT5 is critical to maintain effector CD8+ T cell responses.
Tripathi P, Kurtulus S, Wojciechowski S, Sholl A, Hoebe K, Morris SC, Finkelman FD, Grimes HL, Hildeman DA. Tripathi P, et al. Among authors: kurtulus s. J Immunol. 2010 Aug 15;185(4):2116-24. doi: 10.4049/jimmunol.1000842. Epub 2010 Jul 19. J Immunol. 2010. PMID: 20644163 Free PMC article.
A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.
Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JYH, Nevin J, Herbst RH, Yanai I, Rozenblatt-Rosen O, Kuchroo VK, Regev A, Anderson AC. Singer M, et al. Among authors: kurtulus s. Cell. 2016 Sep 8;166(6):1500-1511.e9. doi: 10.1016/j.cell.2016.08.052. Cell. 2016. PMID: 27610572 Free PMC article.
34 results