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A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer.
de Sousa e Melo F, Kurtova AV, Harnoss JM, Kljavin N, Hoeck JD, Hung J, Anderson JE, Storm EE, Modrusan Z, Koeppen H, Dijkgraaf GJ, Piskol R, de Sauvage FJ. de Sousa e Melo F, et al. Among authors: kurtova av. Nature. 2017 Mar 29;543(7647):676-680. doi: 10.1038/nature21713. Nature. 2017. PMID: 28358093
Stem cell plasticity enables hair regeneration following Lgr5+ cell loss.
Hoeck JD, Biehs B, Kurtova AV, Kljavin NM, de Sousa E Melo F, Alicke B, Koeppen H, Modrusan Z, Piskol R, de Sauvage FJ. Hoeck JD, et al. Among authors: kurtova av. Nat Cell Biol. 2017 Jun;19(6):666-676. doi: 10.1038/ncb3535. Epub 2017 May 29. Nat Cell Biol. 2017. PMID: 28553937
Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova AV, Heinlein M, Haas S, Velten L, Dijkgraaf GJP, Storm EE, Kljavin NM, Boumahdi S, Himmels P, Herault A, Mancini A, Koeppen H, Dail M, Yan Q, Zhang J, Koch U, Radtke F, Modrusan Z, Metcalfe C, Piskol R, de Sauvage FJ. Kurtova AV, et al. Blood Adv. 2023 Feb 28;7(4):491-507. doi: 10.1182/bloodadvances.2022007714. Blood Adv. 2023. PMID: 35914228 Free PMC article.
Cellular Hierarchy as a Determinant of Tumor Sensitivity to Chemotherapy.
Rodriguez-Brenes IA, Kurtova AV, Lin C, Lee YC, Xiao J, Mims M, Chan KS, Wodarz D. Rodriguez-Brenes IA, et al. Among authors: kurtova av. Cancer Res. 2017 May 1;77(9):2231-2241. doi: 10.1158/0008-5472.CAN-16-2434. Epub 2017 Feb 24. Cancer Res. 2017. PMID: 28235762 Free PMC article.
Three differentiation states risk-stratify bladder cancer into distinct subtypes.
Volkmer JP, Sahoo D, Chin RK, Ho PL, Tang C, Kurtova AV, Willingham SB, Pazhanisamy SK, Contreras-Trujillo H, Storm TA, Lotan Y, Beck AH, Chung BI, Alizadeh AA, Godoy G, Lerner SP, van de Rijn M, Shortliffe LD, Weissman IL, Chan KS. Volkmer JP, et al. Among authors: kurtova av. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2078-83. doi: 10.1073/pnas.1120605109. Epub 2012 Jan 19. Proc Natl Acad Sci U S A. 2012. PMID: 22308455 Free PMC article.
16 results