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Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors.
Horan KA, Hansen K, Jakobsen MR, Holm CK, Søby S, Unterholzner L, Thompson M, West JA, Iversen MB, Rasmussen SB, Ellermann-Eriksen S, Kurt-Jones E, Landolfo S, Damania B, Melchjorsen J, Bowie AG, Fitzgerald KA, Paludan SR. Horan KA, et al. J Immunol. 2013 Mar 1;190(5):2311-9. doi: 10.4049/jimmunol.1202749. Epub 2013 Jan 23. J Immunol. 2013. PMID: 23345332 Free PMC article.
Herpes simplex virus and toll-like receptors.
Finberg RW, Knipe DM, Kurt-Jones EA. Finberg RW, et al. Viral Immunol. 2005;18(3):457-65. doi: 10.1089/vim.2005.18.457. Viral Immunol. 2005. PMID: 16212524 Review.
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