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Improved survival with MEK inhibition in BRAF-mutated melanoma.
Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, Demidov LV, Hassel JC, Rutkowski P, Mohr P, Dummer R, Trefzer U, Larkin JM, Utikal J, Dreno B, Nyakas M, Middleton MR, Becker JC, Casey M, Sherman LJ, Wu FS, Ouellet D, Martin AM, Patel K, Schadendorf D; METRIC Study Group. Flaherty KT, et al. N Engl J Med. 2012 Jul 12;367(2):107-14. doi: 10.1056/NEJMoa1203421. Epub 2012 Jun 4. N Engl J Med. 2012. PMID: 22663011 Free article. Clinical Trial.
Allostery in Hsp70 chaperones is transduced by subdomain rotations.
Bhattacharya A, Kurochkin AV, Yip GN, Zhang Y, Bertelsen EB, Zuiderweg ER. Bhattacharya A, et al. Among authors: kurochkin av. J Mol Biol. 2009 May 8;388(3):475-90. doi: 10.1016/j.jmb.2009.01.062. Epub 2009 Feb 4. J Mol Biol. 2009. PMID: 19361428 Free PMC article.
Functional dynamics in the active site of the ribonuclease binase.
Wang L, Pang Y, Holder T, Brender JR, Kurochkin AV, Zuiderweg ER. Wang L, et al. Among authors: kurochkin av. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7684-9. doi: 10.1073/pnas.121069998. Proc Natl Acad Sci U S A. 2001. PMID: 11438724 Free PMC article.
35 results