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Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Turcu AL, Companys-Alemany J, Phillips MB, Patel DS, Griñán-Ferré C, Loza MI, Brea JM, Pérez B, Soto D, Sureda FX, Kurnikova MG, Johnson JW, Pallàs M, Vázquez S. Turcu AL, et al. Among authors: kurnikova mg. Eur J Med Chem. 2022 Jun 5;236:114354. doi: 10.1016/j.ejmech.2022.114354. Epub 2022 Apr 8. Eur J Med Chem. 2022. PMID: 35453065 Free PMC article.
Opening of glutamate receptor channel to subconductance levels.
Yelshanskaya MV, Patel DS, Kottke CM, Kurnikova MG, Sobolevsky AI. Yelshanskaya MV, et al. Among authors: kurnikova mg. Nature. 2022 May;605(7908):172-178. doi: 10.1038/s41586-022-04637-w. Epub 2022 Apr 20. Nature. 2022. PMID: 35444281 Free PMC article.
Inhibition of NMDA receptors through a membrane-to-channel path.
Wilcox MR, Nigam A, Glasgow NG, Narangoda C, Phillips MB, Patel DS, Mesbahi-Vasey S, Turcu AL, Vázquez S, Kurnikova MG, Johnson JW. Wilcox MR, et al. Among authors: kurnikova mg. Nat Commun. 2022 Jul 15;13(1):4114. doi: 10.1038/s41467-022-31817-z. Nat Commun. 2022. PMID: 35840593 Free PMC article.
Structural mechanisms of TRPM7 activation and inhibition.
Nadezhdin KD, Correia L, Narangoda C, Patel DS, Neuberger A, Gudermann T, Kurnikova MG, Chubanov V, Sobolevsky AI. Nadezhdin KD, et al. Among authors: kurnikova mg. Nat Commun. 2023 May 8;14(1):2639. doi: 10.1038/s41467-023-38362-3. Nat Commun. 2023. PMID: 37156763 Free PMC article.
Protein-Ligand Binding Free-Energy Calculations with ARROW─A Purely First-Principles Parameterized Polarizable Force Field.
Nawrocki G, Leontyev I, Sakipov S, Darkhovskiy M, Kurnikov I, Pereyaslavets L, Kamath G, Voronina E, Butin O, Illarionov A, Olevanov M, Kostikov A, Ivahnenko I, Patel DS, Sankaranarayanan SKRS, Kurnikova MG, Lock C, Crooks GE, Levitt M, Kornberg RD, Fain B. Nawrocki G, et al. Among authors: kurnikova mg. J Chem Theory Comput. 2022 Dec 13;18(12):7751-7763. doi: 10.1021/acs.jctc.2c00930. Epub 2022 Dec 2. J Chem Theory Comput. 2022. PMID: 36459593 Free PMC article.
61 results