Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

73 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease.
Czarnota-Łydka K, Sudoł-Tałaj S, Kucwaj-Brysz K, Kurczab R, Satała G, de Candia M, Samarelli F, Altomare CD, Carocci A, Barbarossa A, Żesławska E, Głuch-Lutwin M, Mordyl B, Kubacka M, Wilczyńska-Zawal N, Jastrzębska-Więsek M, Partyka A, Khan N, Więcek M, Nitek W, Honkisz-Orzechowska E, Latacz G, Wesołowska A, Carrieri A, Handzlik J. Czarnota-Łydka K, et al. Among authors: kurczab r. Eur J Med Chem. 2023 Nov 5;259:115695. doi: 10.1016/j.ejmech.2023.115695. Epub 2023 Jul 30. Eur J Med Chem. 2023. PMID: 37567058 Free article.
The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT₇ receptor antagonists.
Zajdel P, Kurczab R, Grychowska K, Satała G, Pawłowski M, Bojarski AJ. Zajdel P, et al. Among authors: kurczab r. Eur J Med Chem. 2012 Oct;56:348-60. doi: 10.1016/j.ejmech.2012.07.043. Epub 2012 Aug 4. Eur J Med Chem. 2012. PMID: 22926225
Solid-supported synthesis, molecular modeling, and biological activity of long-chain arylpiperazine derivatives with cyclic amino acid amide fragments as 5-HT(7) and 5-HT(1A) receptor ligands.
Canale V, Guzik P, Kurczab R, Verdie P, Satała G, Kubica B, Pawłowski M, Martinez J, Subra G, Bojarski AJ, Zajdel P. Canale V, et al. Among authors: kurczab r. Eur J Med Chem. 2014 May 6;78:10-22. doi: 10.1016/j.ejmech.2014.03.005. Epub 2014 Mar 5. Eur J Med Chem. 2014. PMID: 24675176
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT(7) and 5-HT(1A) receptor ligands.
Salerno L, Pittalà V, Modica MN, Siracusa MA, Intagliata S, Cagnotto A, Salmona M, Kurczab R, Bojarski AJ, Romeo G. Salerno L, et al. Among authors: kurczab r. Eur J Med Chem. 2014 Oct 6;85:716-26. doi: 10.1016/j.ejmech.2014.08.023. Epub 2014 Aug 7. Eur J Med Chem. 2014. PMID: 25128671
Towards novel 5-HT7versus 5-HT1A receptor ligands among LCAPs with cyclic amino acid amide fragments: design, synthesis, and antidepressant properties. Part II.
Canale V, Kurczab R, Partyka A, Satała G, Witek J, Jastrzębska-Więsek M, Pawłowski M, Bojarski AJ, Wesołowska A, Zajdel P. Canale V, et al. Among authors: kurczab r. Eur J Med Chem. 2015 Mar 6;92:202-11. doi: 10.1016/j.ejmech.2014.12.041. Epub 2014 Dec 24. Eur J Med Chem. 2015. PMID: 25555143
Towards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties.
Canale V, Kurczab R, Partyka A, Satała G, Lenda T, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Zajdel P. Canale V, et al. Among authors: kurczab r. Eur J Med Chem. 2016 Jan 27;108:334-346. doi: 10.1016/j.ejmech.2015.11.040. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698537
Novel 5-HT7R antagonists, arylsulfonamide derivatives of (aryloxy)propyl piperidines: Add-on effect to the antidepressant activity of SSRI and DRI, and pro-cognitive profile.
Canale V, Partyka A, Kurczab R, Krawczyk M, Kos T, Satała G, Kubica B, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Popik P, Zajdel P. Canale V, et al. Among authors: kurczab r. Bioorg Med Chem. 2017 May 15;25(10):2789-2799. doi: 10.1016/j.bmc.2017.03.057. Epub 2017 Mar 29. Bioorg Med Chem. 2017. PMID: 28391970
The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine.
Łażewska D, Kurczab R, Więcek M, Kamińska K, Satała G, Jastrzębska-Więsek M, Partyka A, Bojarski AJ, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Łażewska D, et al. Among authors: kurczab r. Eur J Med Chem. 2017 Jul 28;135:117-124. doi: 10.1016/j.ejmech.2017.04.033. Epub 2017 Apr 13. Eur J Med Chem. 2017. PMID: 28441580
73 results