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Loss-of-function mutations in the co-chaperone protein BAG5 cause dilated cardiomyopathy requiring heart transplantation.
Hakui H, Kioka H, Miyashita Y, Nishimura S, Matsuoka K, Kato H, Tsukamoto O, Kuramoto Y, Takuwa A, Takahashi Y, Saito S, Ohta K, Asanuma H, Fu HY, Shinomiya H, Yamada N, Ohtani T, Sawa Y, Kitakaze M, Takashima S, Sakata Y, Asano Y. Hakui H, et al. Among authors: kuramoto y. Sci Transl Med. 2022 Jan 19;14(628):eabf3274. doi: 10.1126/scitranslmed.abf3274. Epub 2022 Jan 19. Sci Transl Med. 2022. PMID: 35044787
Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O.
Okada K, Naito AT, Higo T, Nakagawa A, Shibamoto M, Sakai T, Hashimoto A, Kuramoto Y, Sumida T, Nomura S, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Morimoto S, Sakata Y, Shiojima I, Komuro I. Okada K, et al. Among authors: kuramoto y. Circ Heart Fail. 2015 Jul;8(4):799-808. doi: 10.1161/CIRCHEARTFAILURE.114.001958. Epub 2015 Jun 2. Circ Heart Fail. 2015. PMID: 26038536
Generation of Induced Pluripotent Stem Cells From Patients With Duchenne Muscular Dystrophy and Their Induction to Cardiomyocytes.
Hashimoto A, Naito AT, Lee JK, Kitazume-Taneike R, Ito M, Yamaguchi T, Nakata R, Sumida T, Okada K, Nakagawa A, Higo T, Kuramoto Y, Sakai T, Tominaga K, Okinaga T, Kogaki S, Ozono K, Miyagawa S, Sawa Y, Sakata Y, Morita H, Umezawa A, Komuro I. Hashimoto A, et al. Among authors: kuramoto y. Int Heart J. 2016;57(1):112-7. doi: 10.1536/ihj.15-376. Epub 2015 Dec 17. Int Heart J. 2016. PMID: 26673445 Free article.
DNA single-strand break-induced DNA damage response causes heart failure.
Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I. Higo T, et al. Among authors: kuramoto y. Nat Commun. 2017 Apr 24;8:15104. doi: 10.1038/ncomms15104. Nat Commun. 2017. PMID: 28436431 Free PMC article.
Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy.
Sakai T, Naito AT, Kuramoto Y, Ito M, Okada K, Higo T, Nakagawa A, Shibamoto M, Yamaguchi T, Sumida T, Nomura S, Umezawa A, Miyagawa S, Sawa Y, Morita H, Lee JK, Shiojima I, Sakata Y, Komuro I. Sakai T, et al. Among authors: kuramoto y. Int Heart J. 2018 Sep 26;59(5):1096-1105. doi: 10.1536/ihj.17-730. Epub 2018 Aug 11. Int Heart J. 2018. PMID: 30101858 Free article.
The CR9 element is a novel mechanical load-responsive enhancer that regulates natriuretic peptide genes expression.
Miyashita Y, Tsukamoto O, Matsuoka K, Kamikubo K, Kuramoto Y, Ying Fu H, Tsubota T, Hasuike H, Takayama T, Ito H, Hitsumoto T, Okamoto C, Kioka H, Oya R, Shinomiya H, Hakui H, Shintani Y, Kato H, Kitakaze M, Sakata Y, Asano Y, Takashima S. Miyashita Y, et al. Among authors: kuramoto y. FASEB J. 2021 Apr;35(4):e21495. doi: 10.1096/fj.202002111RR. FASEB J. 2021. PMID: 33689182
206 results