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An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Among authors: kuo cj. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC. Rosenbluh J, et al. Among authors: kuo cj. Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Cell. 2012. PMID: 23245941 Free PMC article.
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity.
Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng ZF, Kaddis JS, Han A, Roelf K, Calderon RI, Cynn E, Hu X, Mandleywala K, Wilhelmy J, Grimes SM, Corney DC, Boutet SC, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy MAS, Jain R, Cartwright CA, Niland JC, Hong YK, Carrington J, Breault DT, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, Kuo CJ. Yan KS, et al. Among authors: kuo cj. Cell Stem Cell. 2017 Jul 6;21(1):78-90.e6. doi: 10.1016/j.stem.2017.06.014. Cell Stem Cell. 2017. PMID: 28686870 Free PMC article.
Organoids lead the cancer attack.
Smith AR, Kuo CJ. Smith AR, et al. Among authors: kuo cj. Nat Med. 2017 Dec 7;23(12):1399-1400. doi: 10.1038/nm.4454. Nat Med. 2017. PMID: 29216041 Free PMC article.
Organoids reveal cancer dynamics.
Kuo CJ, Curtis C. Kuo CJ, et al. Nature. 2018 Apr;556(7702):441-442. doi: 10.1038/d41586-018-03841-x. Nature. 2018. PMID: 29686366 No abstract available.
The Intestinal Stem Cell Niche: Homeostasis and Adaptations.
Santos AJM, Lo YH, Mah AT, Kuo CJ. Santos AJM, et al. Among authors: kuo cj. Trends Cell Biol. 2018 Dec;28(12):1062-1078. doi: 10.1016/j.tcb.2018.08.001. Epub 2018 Sep 5. Trends Cell Biol. 2018. PMID: 30195922 Free PMC article. Review.
Organoid Modeling of the Tumor Immune Microenvironment.
Neal JT, Li X, Zhu J, Giangarra V, Grzeskowiak CL, Ju J, Liu IH, Chiou SH, Salahudeen AA, Smith AR, Deutsch BC, Liao L, Zemek AJ, Zhao F, Karlsson K, Schultz LM, Metzner TJ, Nadauld LD, Tseng YY, Alkhairy S, Oh C, Keskula P, Mendoza-Villanueva D, De La Vega FM, Kunz PL, Liao JC, Leppert JT, Sunwoo JB, Sabatti C, Boehm JS, Hahn WC, Zheng GXY, Davis MM, Kuo CJ. Neal JT, et al. Among authors: kuo cj. Cell. 2018 Dec 13;175(7):1972-1988.e16. doi: 10.1016/j.cell.2018.11.021. Cell. 2018. PMID: 30550791 Free PMC article.
535 results