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An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin.
Garner AP, Bialucha CU, Sprague ER, Garrett JT, Sheng Q, Li S, Sineshchekova O, Saxena P, Sutton CR, Chen D, Chen Y, Wang H, Liang J, Das R, Mosher R, Gu J, Huang A, Haubst N, Zehetmeier C, Haberl M, Elis W, Kunz C, Heidt AB, Herlihy K, Murtie J, Schuller A, Arteaga CL, Sellers WR, Ettenberg SA. Garner AP, et al. Among authors: kunz c. Cancer Res. 2013 Oct 1;73(19):6024-35. doi: 10.1158/0008-5472.CAN-13-1198. Epub 2013 Aug 8. Cancer Res. 2013. PMID: 23928993 Free PMC article.
Peptide aptamers: recent developments for cancer therapy.
Borghouts C, Kunz C, Groner B. Borghouts C, et al. Among authors: kunz c. Expert Opin Biol Ther. 2005 Jun;5(6):783-97. doi: 10.1517/14712598.5.6.783. Expert Opin Biol Ther. 2005. PMID: 15952909 Review.
Peptide aptamer libraries.
Borghouts C, Kunz C, Groner B. Borghouts C, et al. Among authors: kunz c. Comb Chem High Throughput Screen. 2008 Feb;11(2):135-45. doi: 10.2174/138620708783744462. Comb Chem High Throughput Screen. 2008. PMID: 18336207 Review.
671 results