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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.
Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi B, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Audu CO, et al. Among authors: kunkel sl. Cell Mol Immunol. 2022 Nov;19(11):1251-1262. doi: 10.1038/s41423-022-00919-5. Epub 2022 Sep 20. Cell Mol Immunol. 2022. PMID: 36127466 Free PMC article.
Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation.
Ito T, Schaller M, Raymond T, Joshi AD, Coelho AL, Frantz FG, Carson WF 4th, Hogaboam CM, Lukacs NW, Standiford TJ, Phan SH, Chensue SW, Kunkel SL. Ito T, et al. Among authors: kunkel sl. Am J Respir Crit Care Med. 2009 Dec 15;180(12):1227-38. doi: 10.1164/rccm.200906-0892OC. Epub 2009 Sep 24. Am J Respir Crit Care Med. 2009. PMID: 19797157 Free PMC article.
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.
Kittan NA, Allen RM, Dhaliwal A, Cavassani KA, Schaller M, Gallagher KA, Carson WF 4th, Mukherjee S, Grembecka J, Cierpicki T, Jarai G, Westwick J, Kunkel SL, Hogaboam CM. Kittan NA, et al. Among authors: kunkel sl. PLoS One. 2013 Oct 21;8(10):e78045. doi: 10.1371/journal.pone.0078045. eCollection 2013. PLoS One. 2013. PMID: 24205083 Free PMC article.
683 results