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An engineering strategy to target activated EGFR with CAR T cells.
Dobersberger M, Sumesgutner D, Zajc CU, Salzer B, Laurent E, Emminger D, Sylvander E, Lehner E, Teufl M, Seigner J, Bobbili MR, Kunert R, Lehner M, Traxlmayr MW. Dobersberger M, et al. Among authors: kunert r. Cell Rep Methods. 2024 Apr 22;4(4):100728. doi: 10.1016/j.crmeth.2024.100728. Epub 2024 Mar 15. Cell Rep Methods. 2024. PMID: 38492569 Free PMC article.
Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
Garner-Spitzer E, Wagner A, Gudipati V, Schoetta AM, Orola-Taus M, Kundi M, Kunert R, Mayrhofer P, Huppa JB, Stockinger H, Carsetti R, Gattinger P, Valenta R, Kratzer B, Sehgal ANA, Pickl WF, Reinisch W, Novacek G, Wiedermann U. Garner-Spitzer E, et al. Among authors: kunert r. EBioMedicine. 2023 Oct;96:104788. doi: 10.1016/j.ebiom.2023.104788. Epub 2023 Sep 4. EBioMedicine. 2023. PMID: 37672867 Free PMC article.
Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Martin GM, Russell RA, Mundsperger P, Harris S, Jovanoska L, Trajano LF, Schiffner T, Fabian K, Tolazzi M, Scarlatti G, McFarlane L, Cheeseman H, Aldon Y, Schermer EE, Breemen M, Sliepen K, Katinger D, Kunert R, Sanders RW, Shattock R, Ward AB, Sattentau QJ. Martin GM, et al. Among authors: kunert r. NPJ Vaccines. 2023 Jul 13;8(1):101. doi: 10.1038/s41541-023-00696-w. NPJ Vaccines. 2023. PMID: 37443366 Free PMC article.
Biophysical Characterization of the Oligomeric States of Recombinant Immunoglobulins Type-M and Their C1q-Binding Kinetics by Biolayer Interferometry.
Chouquet A, Pinto AJ, Hennicke J, Ling WL, Bally I, Schwaigerlehner L, Thielens NM, Kunert R, Reiser JB. Chouquet A, et al. Among authors: kunert r. Front Bioeng Biotechnol. 2022 May 24;10:816275. doi: 10.3389/fbioe.2022.816275. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 35685087 Free PMC article.
SARS-CoV-2-Specific Antibody (Ab) Levels and the Kinetic of Ab Decline Determine Ab Persistence Over 1 Year.
Garner-Spitzer E, Wagner A, Kundi M, Stockinger H, Ohradanova-Repic A, Gebetsberger L, Schoetta AM, Gudipati V, Huppa JB, Kunert R, Mayrhofer P, Kreil TR, Farcet MR, Hoeltl E, Wiedermann U. Garner-Spitzer E, et al. Among authors: kunert r. Front Med (Lausanne). 2022 Feb 15;9:822316. doi: 10.3389/fmed.2022.822316. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35242786 Free PMC article.
Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati V, Rydzek J, Doel-Perez I, Gonçalves VDR, Scharf L, Königsberger S, Lobner E, Kunert R, Einsele H, Stockinger H, Hudecek M, Huppa JB. Gudipati V, et al. Among authors: kunert r. Nat Immunol. 2020 Aug;21(8):848-856. doi: 10.1038/s41590-020-0719-0. Epub 2020 Jul 6. Nat Immunol. 2020. PMID: 32632291
145 results