Kumita JR - Search Results

1

Structural Characterization of Covalently Stabilized Human Cystatin C Oligomers.

Chrabąszczewska M, Sieradzan AK, Rodziewicz-Motowidło S, Grubb A, Dobson CM, Kumita JR, Kozak M. Chrabąszczewska M, et al. Among authors: kumita jr. Int J Mol Sci. 2020 Aug 15;21(16):5860. doi: 10.3390/ijms21165860. Int J Mol Sci. 2020. PMID: 32824145 Free PMC article.

2

Normal and aberrant biological self-assembly: Insights from studies of human lysozyme and its amyloidogenic variants.

Dumoulin M, Kumita JR, Dobson CM. Dumoulin M, et al. Among authors: kumita jr. Acc Chem Res. 2006 Sep;39(9):603-10. doi: 10.1021/ar050070g. Acc Chem Res. 2006. PMID: 16981676 Free article.

3

The influence of novel gemini surfactants containing cycloalkyl side-chains on the structural phases of DNA in solution.

Pietralik Z, Kumita JR, Dobson CM, Kozak M. Pietralik Z, et al. Among authors: kumita jr. Colloids Surf B Biointerfaces. 2015 Jul 1;131:83-92. doi: 10.1016/j.colsurfb.2015.04.042. Epub 2015 Apr 27. Colloids Surf B Biointerfaces. 2015. PMID: 25969417

4

Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers.

Limbocker R, Mannini B, Cataldi R, Chhangur S, Wright AK, Kreiser RP, Albright JA, Chia S, Habchi J, Sormanni P, Kumita JR, Ruggeri FS, Dobson CM, Chiti F, Aprile FA, Vendruscolo M. Limbocker R, et al. Among authors: kumita jr. Int J Mol Sci. 2020 Jun 25;21(12):4542. doi: 10.3390/ijms21124542. Int J Mol Sci. 2020. PMID: 32630615 Free PMC article.

5

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.

Xu CK, Castellana-Cruz M, Chen SW, Du Z, Meisl G, Levin A, Mannini B, Itzhaki LS, Knowles TPJ, Dobson CM, Cremades N, Kumita JR. Xu CK, et al. Among authors: kumita jr. Molecules. 2022 Feb 15;27(4):1293. doi: 10.3390/molecules27041293. Molecules. 2022. PMID: 35209093 Free PMC article.

6

Rationalising lysozyme amyloidosis: insights from the structure and solution dynamics of T70N lysozyme.

Johnson RJ, Christodoulou J, Dumoulin M, Caddy GL, Alcocer MJ, Murtagh GJ, Kumita JR, Larsson G, Robinson CV, Archer DB, Luisi B, Dobson CM. Johnson RJ, et al. Among authors: kumita jr. J Mol Biol. 2005 Sep 30;352(4):823-36. doi: 10.1016/j.jmb.2005.07.040. J Mol Biol. 2005. PMID: 16126226 Free article.

7

The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species.

Kumita JR, Poon S, Caddy GL, Hagan CL, Dumoulin M, Yerbury JJ, Stewart EM, Robinson CV, Wilson MR, Dobson CM. Kumita JR, et al. J Mol Biol. 2007 May 25;369(1):157-67. doi: 10.1016/j.jmb.2007.02.095. Epub 2007 Mar 7. J Mol Biol. 2007. PMID: 17407782 Free article.

8

Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide.

Aran Terol P, Kumita JR, Hook SC, Dobson CM, Esbjörner EK. Aran Terol P, et al. Among authors: kumita jr. Biochem Biophys Res Commun. 2015 Dec 25;468(4):696-701. doi: 10.1016/j.bbrc.2015.11.018. Epub 2015 Nov 10. Biochem Biophys Res Commun. 2015. PMID: 26551456 Free PMC article.

9

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.

Limbocker R, Mannini B, Ruggeri FS, Cascella R, Xu CK, Perni M, Chia S, Chen SW, Habchi J, Bigi A, Kreiser RP, Wright AK, Albright JA, Kartanas T, Kumita JR, Cremades N, Zasloff M, Cecchi C, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM. Limbocker R, et al. Among authors: kumita jr. Commun Biol. 2020 Aug 13;3(1):435. doi: 10.1038/s42003-020-01140-8. Commun Biol. 2020. PMID: 32792544 Free PMC article.

10

Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution.

Arter WE, Xu CK, Castellana-Cruz M, Herling TW, Krainer G, Saar KL, Kumita JR, Dobson CM, Knowles TPJ. Arter WE, et al. Among authors: kumita jr. Nano Lett. 2020 Nov 11;20(11):8163-8169. doi: 10.1021/acs.nanolett.0c03260. Epub 2020 Oct 20. Nano Lett. 2020. PMID: 33079553 Free PMC article.

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