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Mast cells: Therapeutic targets for COVID-19 and beyond.
Lam HY, Tergaonkar V, Kumar AP, Ahn KS. Lam HY, et al. Among authors: kumar ap. IUBMB Life. 2021 Nov;73(11):1278-1292. doi: 10.1002/iub.2552. Epub 2021 Sep 21. IUBMB Life. 2021. PMID: 34467628 Free PMC article. Review.
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4.
Manu KA, Shanmugam MK, Rajendran P, Li F, Ramachandran L, Hay HS, Kannaiyan R, Swamy SN, Vali S, Kapoor S, Ramesh B, Bist P, Koay ES, Lim LH, Ahn KS, Kumar AP, Sethi G. Manu KA, et al. Among authors: kumar ap. Mol Cancer. 2011 Sep 1;10:107. doi: 10.1186/1476-4598-10-107. Mol Cancer. 2011. PMID: 21880153 Free PMC article.
Multifaceted link between cancer and inflammation.
Sethi G, Shanmugam MK, Ramachandran L, Kumar AP, Tergaonkar V. Sethi G, et al. Among authors: kumar ap. Biosci Rep. 2012 Feb;32(1):1-15. doi: 10.1042/BSR20100136. Biosci Rep. 2012. PMID: 21981137 Review.
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.
Rajendran P, Li F, Shanmugam MK, Kannaiyan R, Goh JN, Wong KF, Wang W, Khin E, Tergaonkar V, Kumar AP, Luk JM, Sethi G. Rajendran P, et al. Among authors: kumar ap. Cancer Prev Res (Phila). 2012 Apr;5(4):631-43. doi: 10.1158/1940-6207.CAPR-11-0420. Epub 2012 Feb 27. Cancer Prev Res (Phila). 2012. PMID: 22369852
Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G. Ramachandran L, et al. Among authors: kumar ap. J Biol Chem. 2012 Nov 2;287(45):38028-40. doi: 10.1074/jbc.M112.388702. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992727 Free PMC article.
Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.
Subramaniam A, Shanmugam MK, Perumal E, Li F, Nachiyappan A, Dai X, Swamy SN, Ahn KS, Kumar AP, Tan BK, Hui KM, Sethi G. Subramaniam A, et al. Among authors: kumar ap. Biochim Biophys Acta. 2013 Jan;1835(1):46-60. doi: 10.1016/j.bbcan.2012.10.002. Epub 2012 Oct 26. Biochim Biophys Acta. 2013. PMID: 23103770 Review.
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Subramaniam A, Loo SY, Rajendran P, Manu KA, Perumal E, Li F, Shanmugam MK, Siveen KS, Park JI, Ahn KS, Hui KM, Kumar AP, Sethi G. Subramaniam A, et al. Among authors: kumar ap. Apoptosis. 2013 Oct;18(10):1175-87. doi: 10.1007/s10495-013-0851-5. Apoptosis. 2013. PMID: 23700228
432 results