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In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates.
Patel A, Rosenke K, Parzych EM, Feldmann F, Bharti S, Griffin AJ, Schouest B, Lewis M, Choi J, Chokkalingam N, Machado V, Smith BJ, Frase D, Ali AR, Lovaglio J, Nguyen B, Hanley PW, Walker SN, Gary EN, Kulkarni A, Generotti A, Francica JR, Rosenthal K, Kulp DW, Esser MT, Smith TRF, Shaia C, Weiner DB, Feldmann H. Patel A, et al. Among authors: kulp dw. Emerg Microbes Infect. 2024 Dec;13(1):2294860. doi: 10.1080/22221751.2023.2294860. Epub 2024 Feb 28. Emerg Microbes Infect. 2024. PMID: 38165394 Free PMC article.
Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination.
Parisian AD, Barratt SA, Hodges-Gallagher L, Ortega FE, Peña G, Sapugay J, Robello B, Sun R, Kulp D, Palanisamy GS, Myles DC, Kushner PJ, Harmon CL. Parisian AD, et al. Among authors: kulp d. Mol Cancer Ther. 2024 Mar 4;23(3):285-300. doi: 10.1158/1535-7163.MCT-23-0351. Mol Cancer Ther. 2024. PMID: 38102750 Free PMC article.
Enhancing Partnerships of Institutions and Journals to Address Concerns About Research Misconduct: Recommendations From a Working Group of Institutional Research Integrity Officers and Journal Editors and Publishers.
Garfinkel S, Alam S, Baskin P, Bennett C, Carruthers B, Engler J, Flanagin A, Garrity S, Graf C, Imperiale MJ, King C, Kleinert S, Kulp D, Mankowski C, Nugent N, Pulvirenti T, Qualkenbush L, Sobiecki E, Wainstock D, Wilfong E, Wold L, Yucel J. Garfinkel S, et al. Among authors: kulp d. JAMA Netw Open. 2023 Jun 1;6(6):e2320796. doi: 10.1001/jamanetworkopen.2023.20796. JAMA Netw Open. 2023. PMID: 37378978 Free article.
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo.
Tursi NJ, Xu Z, Helble M, Walker S, Liaw K, Chokkalingam N, Kannan T, Wu Y, Tello-Ruiz E, Park DH, Zhu X, Wise MC, Smith TRF, Majumdar S, Kossenkov A, Kulp DW, Weiner DB. Tursi NJ, et al. Among authors: kulp dw. Front Immunol. 2023 Feb 23;14:1072810. doi: 10.3389/fimmu.2023.1072810. eCollection 2023. Front Immunol. 2023. PMID: 36911698 Free PMC article.
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Parzych EM, Du J, Ali AR, Schultheis K, Frase D, Smith TRF, Cui J, Chokkalingam N, Tursi NJ, Andrade VM, Warner BM, Gary EN, Li Y, Choi J, Eisenhauer J, Maricic I, Kulkarni A, Chu JD, Villafana G, Rosenthal K, Ren K, Francica JR, Wootton SK, Tebas P, Kobasa D, Broderick KE, Boyer JD, Esser MT, Pallesen J, Kulp DW, Patel A, Weiner DB. Parzych EM, et al. Among authors: kulp dw. Nat Commun. 2022 Oct 6;13(1):5886. doi: 10.1038/s41467-022-33309-6. Nat Commun. 2022. PMID: 36202799 Free PMC article.
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo.
Gary EN, Tursi NJ, Warner B, Parzych EM, Ali AR, Frase D, Moffat E, Embury-Hyatt C, Smith TRF, Broderick KE, Humeau L, Kobasa D, Patel A, Kulp DW, Weiner DB. Gary EN, et al. Among authors: kulp dw. Cell Rep Med. 2022 Jul 19;3(7):100693. doi: 10.1016/j.xcrm.2022.100693. Epub 2022 Jun 28. Cell Rep Med. 2022. PMID: 35839767 Free PMC article.
141 results