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Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity.
Kooijman S, van den Berg R, Ramkisoensing A, Boon MR, Kuipers EN, Loef M, Zonneveld TC, Lucassen EA, Sips HC, Chatzispyrou IA, Houtkooper RH, Meijer JH, Coomans CP, Biermasz NR, Rensen PC. Kooijman S, et al. Among authors: kuipers en. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6748-53. doi: 10.1073/pnas.1504239112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964318 Free PMC article.
Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.
Liu J, Kuipers EN, Sips HCM, Dorleijn JC, van Dam AD, Christodoulides C, Karpe F, Zhou G, Boon MR, Rensen PCN, de Vries AAF, Kooijman S. Liu J, et al. Among authors: kuipers en. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158511. doi: 10.1016/j.bbalip.2019.08.007. Epub 2019 Aug 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31465889 Free article.
High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.
Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. Kuipers EN, et al. Front Physiol. 2019 Jan 10;9:1913. doi: 10.3389/fphys.2018.01913. eCollection 2018. Front Physiol. 2019. PMID: 30687125 Free PMC article.
Estradiol-driven metabolism in transwomen associates with reduced circulating extracellular vesicle microRNA-224/452.
Florijn BW, Duijs JMGJ, Klaver M, Kuipers EN, Kooijman S, Prins J, Zhang H, Sips HCM, Stam W, Hanegraaf M, Limpens RWAL, Nieuwland R, van Rijn BB, Rabelink TJ, Rensen PCN, den Heijer M, Bijkerk R, van Zonneveld AJ. Florijn BW, et al. Among authors: kuipers en. Eur J Endocrinol. 2021 Aug 27;185(4):539-552. doi: 10.1530/EJE-21-0267. Eur J Endocrinol. 2021. PMID: 34342596 Free PMC article.
Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.
Blondin DP, Nielsen S, Kuipers EN, Severinsen MC, Jensen VH, Miard S, Jespersen NZ, Kooijman S, Boon MR, Fortin M, Phoenix S, Frisch F, Guérin B, Turcotte ÉE, Haman F, Richard D, Picard F, Rensen PCN, Scheele C, Carpentier AC. Blondin DP, et al. Among authors: kuipers en. Cell Metab. 2020 Aug 4;32(2):287-300.e7. doi: 10.1016/j.cmet.2020.07.005. Cell Metab. 2020. PMID: 32755608 Free article.
Androgens modulate glucocorticoid receptor activity in adipose tissue and liver.
Spaanderman DCE, Nixon M, Buurstede JC, Sips HC, Schilperoort M, Kuipers EN, Backer EA, Kooijman S, Rensen PCN, Homer NZM, Walker BR, Meijer OC, Kroon J. Spaanderman DCE, et al. Among authors: kuipers en. J Endocrinol. 2018 Oct 1:JOE-18-0503.R1. doi: 10.1530/JOE-18-0503. Online ahead of print. J Endocrinol. 2018. PMID: 30400038
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