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A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis.
Ostkamp P, Deffner M, Schulte-Mecklenbeck A, Wünsch C, Lu IN, Wu GF, Goelz S, De Jager PL, Kuhlmann T, Gross CC, Klotz L, Meyer Zu Hörste G, Wiendl H, Schneider-Hohendorf T, Schwab N. Ostkamp P, et al. Among authors: kuhlmann t. Sci Transl Med. 2022 Nov 30;14(673):eadc9778. doi: 10.1126/scitranslmed.adc9778. Epub 2022 Nov 30. Sci Transl Med. 2022. PMID: 36449599
VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells.
Schneider-Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, Gross CC, Flanagan K, Sorokin L, Vestweber D, Zarbock A, Schwab N, Wiendl H. Schneider-Hohendorf T, et al. Among authors: kuhlmann t. J Exp Med. 2014 Aug 25;211(9):1833-46. doi: 10.1084/jem.20140540. Epub 2014 Aug 18. J Exp Med. 2014. PMID: 25135296 Free PMC article.
Long-term efficacy of alemtuzumab in polymyositis.
Ruck T, Bittner S, Kuhlmann T, Wiendl H, Meuth SG. Ruck T, et al. Among authors: kuhlmann t. Rheumatology (Oxford). 2015 Mar;54(3):560-2. doi: 10.1093/rheumatology/keu484. Epub 2014 Dec 30. Rheumatology (Oxford). 2015. PMID: 25552256 Free PMC article. No abstract available.
Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.
Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, Hartwig M, Dornmair K, Hohlfeld R, Ziemssen T, Klotz L, Meuth SG, Wiendl H. Gross CC, et al. Among authors: kuhlmann t. Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2973-82. doi: 10.1073/pnas.1524924113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162345 Free PMC article.
211 results