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Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19.
Zumbrun EE, Kaku CI, Dillinger L, Zak SE, Kuehne AI, Bakken RR, Koehler JW, Delp KL, Stefan CP, Kumar R, Kugelman JR, Moreau AM, Zeng X, Dye JM, Herbert AS, Narayan K, Walker LM. Zumbrun EE, et al. Among authors: kugelman jr. Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0135322. doi: 10.1128/aac.01353-22. Epub 2022 Dec 15. Antimicrob Agents Chemother. 2023. PMID: 36519929 Free PMC article.
Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure.
Johnston SC, Ricks KM, Jay A, Raymond JL, Rossi F, Zeng X, Scruggs J, Dyer D, Frick O, Koehler JW, Kuehnert PA, Clements TL, Shoemaker CJ, Coyne SR, Delp KL, Moore J, Berrier K, Esham H, Shamblin J, Sifford W, Fiallos J, Klosterman L, Stevens S, White L, Bowling P, Garcia T, Jensen C, Ghering J, Nyakiti D, Bellanca S, Kearney B, Giles W, Alli N, Paz F, Akers K, Danner D, Barth J, Johnson JA, Durant M, Kim R, Hooper JW, Smith JM, Kugelman JR, Beitzel BF, Gibson KM, Pitt MLM, Minogue TD, Nalca A. Johnston SC, et al. Among authors: kugelman jr. PLoS One. 2021 Feb 2;16(2):e0246366. doi: 10.1371/journal.pone.0246366. eCollection 2021. PLoS One. 2021. PMID: 33529233 Free PMC article.
Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail.
Kugelman JR, Kugelman-Tonos J, Ladner JT, Pettit J, Keeton CM, Nagle ER, Garcia KY, Froude JW, Kuehne AI, Kuhn JH, Bavari S, Zeitlin L, Dye JM, Olinger GG, Sanchez-Lockhart M, Palacios GF. Kugelman JR, et al. Among authors: kugelman tonos j. Cell Rep. 2015 Sep 29;12(12):2111-20. doi: 10.1016/j.celrep.2015.08.038. Epub 2015 Sep 10. Cell Rep. 2015. PMID: 26365189 Free article.
Recent successes in therapeutics for Ebola virus disease: no time for complacency.
Iversen PL, Kane CD, Zeng X, Panchal RG, Warren TK, Radoshitzky SR, Kuhn JH, Mudhasani RR, Cooper CL, Shurtleff AC, Nasar F, Sunay MM, Duplantier AJ, Eaton BP, Zumbrun EE, Bixler SL, Martin S, Meinig JM, Chiang CY, Sanchez-Lockhart M, Palacios GF, Kugelman JR, Martins KA, Pitt ML, Crozier I, Saunders DL. Iversen PL, et al. Among authors: kugelman jr. Lancet Infect Dis. 2020 Sep;20(9):e231-e237. doi: 10.1016/S1473-3099(20)30282-6. Epub 2020 Jun 18. Lancet Infect Dis. 2020. PMID: 32563280 Free PMC article. Review.
On-Demand Patient-Specific Phenotype-to-Genotype Ebola Virus Characterization.
Beitzel BF, Radoshitzky SR, Di Paola N, Brannan JM, Kimmel D, Caviness K, Soloveva V, Yu S, Postnikova EN, Finch CL, Liu H, Prugar L, Bakken R, Dye JM, Kugelman JR, Cunningham JM, Sanchez-Lockhart M, Kuhn JH, Palacios G. Beitzel BF, et al. Among authors: kugelman jr. Viruses. 2021 Oct 6;13(10):2010. doi: 10.3390/v13102010. Viruses. 2021. PMID: 34696439 Free PMC article.
Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis).
Finch CL, Crozier I, Lee JH, Byrum R, Cooper TK, Liang J, Sharer K, Solomon J, Sayre PJ, Kocher G, Bartos C, Aiosa NM, Castro M, Larson PA, Adams R, Beitzel B, Di Paola N, Kugelman JR, Kurtz JR, Burdette T, Nason MC, Feuerstein IM, Palacios G, St Claire MC, Lackemeyer MG, Johnson RF, Braun KM, Ramuta MD, Wada J, Schmaljohn CS, Friedrich TC, O'Connor DH, Kuhn JH. Finch CL, et al. Among authors: kugelman jr. bioRxiv [Preprint]. 2020 May 14:2020.05.14.096727. doi: 10.1101/2020.05.14.096727. bioRxiv. 2020. PMID: 32511338 Free PMC article. Preprint.
Molecular analysis of the 2012 Bundibugyo virus disease outbreak.
Hulseberg CE, Kumar R, Di Paola N, Larson P, Nagle ER, Richardson J, Hanson J, Wauquier N, Fair JN, Makuwa M, Mulembakani P, Muyembe-Tamfum JJ, Schoepp RJ, Sanchez-Lockhart M, Palacios GF, Kuhn JH, Kugelman JR. Hulseberg CE, et al. Among authors: kugelman jr. Cell Rep Med. 2021 Jul 27;2(8):100351. doi: 10.1016/j.xcrm.2021.100351. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467242 Free PMC article.
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Warren TK, et al. Among authors: kugelman jr. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. Epub 2016 Mar 2. Nature. 2016. PMID: 26934220 Free PMC article.
39 results