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The homeobox transcription factor DUXBL controls exit from totipotency.
Vega-Sendino M, Lüttmann FF, Olbrich T, Chen Y, Kuenne C, Stein P, Tillo D, Carey GI, Zhong J, Savy V, Radonova L, Lu T, Saykali B, Kim KP, Domingo CN, Schüler L, Günther S, Bentsen M, Bosnakovski D, Schöler H, Kyba M, Maity TK, Jenkins LM, Looso M, Williams CJ, Kim J, Ruiz S. Vega-Sendino M, et al. Among authors: kuenne c. Nat Genet. 2024 Apr;56(4):697-709. doi: 10.1038/s41588-024-01692-z. Epub 2024 Mar 20. Nat Genet. 2024. PMID: 38509386
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li X, Wu F, Günther S, Looso M, Kuenne C, Zhang T, Wiesnet M, Klatt S, Zukunft S, Fleming I, Poschet G, Wietelmann A, Atzberger A, Potente M, Yuan X, Braun T. Li X, et al. Among authors: kuenne c. Nature. 2023 Oct;622(7983):619-626. doi: 10.1038/s41586-023-06585-5. Epub 2023 Sep 27. Nature. 2023. PMID: 37758950 Free PMC article.
ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth.
Karger A, Mansouri S, Leisegang MS, Weigert A, Günther S, Kuenne C, Wittig I, Zukunft S, Klatt S, Aliraj B, Klotz LV, Winter H, Mahavadi P, Fleming I, Ruppert C, Witte B, Alkoudmani I, Gattenlöhner S, Grimminger F, Seeger W, Pullamsetti SS, Savai R. Karger A, et al. Among authors: kuenne c. EMBO J. 2023 Sep 18;42(18):e111620. doi: 10.15252/embj.2022111620. Epub 2023 Aug 7. EMBO J. 2023. PMID: 37545364 Free PMC article.
The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization.
Zheng X, Sarode P, Weigert A, Turkowski K, Chelladurai P, Günther S, Kuenne C, Winter H, Stenzinger A, Reu S, Grimminger F, Stiewe T, Seeger W, Pullamsetti SS, Savai R. Zheng X, et al. Among authors: kuenne c. Cancer Res. 2023 Jul 14;83(14):2345-2357. doi: 10.1158/0008-5472.CAN-22-1270. Cancer Res. 2023. PMID: 37205635
Targeting Wnt-ß-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling.
Nayakanti SR, Friedrich A, Sarode P, Jafari L, Maroli G, Boehm M, Bourgeois A, Grobs Y, Khassafi F, Kuenne C, Guenther S, Dabral S, Wilhelm J, Weiss A, Wietelmann A, Kojonazarov B, Janssen W, Looso M, de Man F, Provencher S, Tello K, Seeger W, Bonnet S, Savai R, Schermuly RT, Pullamsetti SS. Nayakanti SR, et al. Among authors: kuenne c. Circ Res. 2023 May 26;132(11):1468-1485. doi: 10.1161/CIRCRESAHA.122.321725. Epub 2023 Apr 12. Circ Res. 2023. PMID: 37042252
Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Wu F, Li X, Looso M, Liu H, Ding D, Günther S, Kuenne C, Liu S, Weissmann N, Boettger T, Atzberger A, Kolahian S, Renz H, Offermanns S, Gärtner U, Potente M, Zhou Y, Yuan X, Braun T. Wu F, et al. Among authors: kuenne c. Nat Genet. 2023 Jan;55(1):100-111. doi: 10.1038/s41588-022-01252-3. Epub 2022 Dec 20. Nat Genet. 2023. PMID: 36539616 Free PMC article.
TF-COMB - Discovering grammar of transcription factor binding sites.
Bentsen M, Heger V, Schultheis H, Kuenne C, Looso M. Bentsen M, et al. Among authors: kuenne c. Comput Struct Biotechnol J. 2022 Jul 21;20:4040-4051. doi: 10.1016/j.csbj.2022.07.025. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35983231 Free PMC article.
Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension.
Chelladurai P, Kuenne C, Bourgeois A, Günther S, Valasarajan C, Cherian AV, Rottier RJ, Romanet C, Weigert A, Boucherat O, Eichstaedt CA, Ruppert C, Guenther A, Braun T, Looso M, Savai R, Seeger W, Bauer UM, Bonnet S, Pullamsetti SS. Chelladurai P, et al. Among authors: kuenne c. Sci Transl Med. 2022 Jun 8;14(648):eabe5407. doi: 10.1126/scitranslmed.abe5407. Epub 2022 Jun 8. Sci Transl Med. 2022. PMID: 35675437
58 results