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The renal inflammatory network of nephronophthisis.
Quatredeniers M, Bienaimé F, Ferri G, Isnard P, Porée E, Billot K, Birgy E, Mazloum M, Ceccarelli S, Silbermann F, Braeg S, Nguyen-Khoa T, Salomon R, Gubler MC, Kuehn EW, Saunier S, Viau A. Quatredeniers M, et al. Among authors: kuehn ew. Hum Mol Genet. 2022 Jul 7;31(13):2121-2136. doi: 10.1093/hmg/ddac014. Hum Mol Genet. 2022. PMID: 35043953 Free article.
Primary cilia regulate mTORC1 activity and cell size through Lkb1.
Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW. Boehlke C, et al. Among authors: kuehn ew. Nat Cell Biol. 2010 Nov;12(11):1115-22. doi: 10.1038/ncb2117. Epub 2010 Oct 24. Nat Cell Biol. 2010. PMID: 20972424 Free PMC article.
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS. Hoff S, et al. Among authors: kuehn ew. Nat Genet. 2013 Aug;45(8):951-6. doi: 10.1038/ng.2681. Epub 2013 Jun 23. Nat Genet. 2013. PMID: 23793029 Free PMC article.
Efficient genome editing of differentiated renal epithelial cells.
Hofherr A, Busch T, Huber N, Nold A, Bohn A, Viau A, Bienaimé F, Kuehn EW, Arnold SJ, Köttgen M. Hofherr A, et al. Among authors: kuehn ew. Pflugers Arch. 2017 Feb;469(2):303-311. doi: 10.1007/s00424-016-1924-4. Epub 2016 Dec 16. Pflugers Arch. 2017. PMID: 27987038 Free PMC article.
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler MC, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, Kuehn EW. Viau A, et al. Among authors: kuehn ew. EMBO J. 2018 Aug 1;37(15):e98615. doi: 10.15252/embj.201798615. Epub 2018 Jun 19. EMBO J. 2018. PMID: 29925518 Free PMC article.
Divergent function of polycystin 1 and polycystin 2 in cell size regulation.
Viau A, Kotsis F, Boehlke C, Braeg S, Klein M, Nitschke R, Walz G, Kuehn EW. Viau A, et al. Among authors: kuehn ew. Biochem Biophys Res Commun. 2020 Jan 8;521(2):290-295. doi: 10.1016/j.bbrc.2019.10.074. Epub 2019 Oct 24. Biochem Biophys Res Commun. 2020. PMID: 31668373
43 results