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Neurotoxins from snake venoms and α-conotoxin ImI inhibit functionally active ionotropic γ-aminobutyric acid (GABA) receptors.
Kudryavtsev DS, Shelukhina IV, Son LV, Ojomoko LO, Kryukova EV, Lyukmanova EN, Zhmak MN, Dolgikh DA, Ivanov IA, Kasheverov IE, Starkov VG, Ramerstorfer J, Sieghart W, Tsetlin VI, Utkin YN. Kudryavtsev DS, et al. J Biol Chem. 2015 Sep 11;290(37):22747-58. doi: 10.1074/jbc.M115.648824. Epub 2015 Jul 28. J Biol Chem. 2015. PMID: 26221036 Free PMC article.
Nonconventional three-finger toxin BMLCL from krait Bungarus multicinctus venom with high affinity interacts with nicotinic acetylcholine receptors.
Utkin YN, Kasheverov IE, Kudryavtsev DS, Andreeva TV, Starkov VG, Ziganshin RH, Kuznetsov DV, Anh HN, Thao NT, Khoa NC, Tsetlin VI. Utkin YN, et al. Among authors: kudryavtsev ds. Dokl Biochem Biophys. 2015;464:294-7. doi: 10.1134/S1607672915050099. Epub 2015 Oct 31. Dokl Biochem Biophys. 2015. PMID: 26518551
Scorpion toxins interact with nicotinic acetylcholine receptors.
Kasheverov IE, Oparin PB, Zhmak MN, Egorova NS, Ivanov IA, Gigolaev AM, Nekrasova OV, Serebryakova MV, Kudryavtsev DS, Prokopev NA, Hoang AN, Tsetlin VI, Vassilevski AA, Utkin YN. Kasheverov IE, et al. FEBS Lett. 2019 Oct;593(19):2779-2789. doi: 10.1002/1873-3468.13530. Epub 2019 Jul 18. FEBS Lett. 2019. PMID: 31276191 Free article.
From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs.
Kryukova EV, Egorova NS, Kudryavtsev DS, Lebedev DS, Spirova EN, Zhmak MN, Garifulina AI, Kasheverov IE, Utkin YN, Tsetlin VI. Kryukova EV, et al. Front Pharmacol. 2019 Jul 3;10:748. doi: 10.3389/fphar.2019.00748. eCollection 2019. Front Pharmacol. 2019. PMID: 31333465 Free PMC article.
51 results