Kuchroo V - Search Results

1

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion.

Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, Singer M, Regev A, Kuchroo V. Zhu C, et al. Among authors: kuchroo v. Sci Adv. 2021 Apr 30;7(18):eabd2710. doi: 10.1126/sciadv.abd2710. Print 2021 Apr. Sci Adv. 2021. PMID: 33931442 Free PMC article.

2

Tim-2 regulates T helper type 2 responses and autoimmunity.

Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Chakravarti S, et al. J Exp Med. 2005 Aug 1;202(3):437-44. doi: 10.1084/jem.20050308. Epub 2005 Jul 25. J Exp Med. 2005. PMID: 16043519 Free PMC article.

3

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, Zheng XX, Strom TB, Kuchroo VK. Zhu C, et al. Nat Immunol. 2005 Dec;6(12):1245-52. doi: 10.1038/ni1271. Epub 2005 Nov 13. Nat Immunol. 2005. PMID: 16286920

4

Tim protein structures reveal a unique face for ligand binding.

Anderson AC, Xiao S, Kuchroo VK. Anderson AC, et al. Immunity. 2007 Mar;26(3):273-5. doi: 10.1016/j.immuni.2007.03.004. Immunity. 2007. PMID: 17376389 Free PMC article.

5

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.

Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Xiao S, et al. J Exp Med. 2007 Jul 9;204(7):1691-702. doi: 10.1084/jem.20062498. Epub 2007 Jul 2. J Exp Med. 2007. PMID: 17606630 Free PMC article.

6

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis.

Zhu B, Bando Y, Xiao S, Yang K, Anderson AC, Kuchroo VK, Khoury SJ. Zhu B, et al. J Immunol. 2007 Oct 15;179(8):5228-37. doi: 10.4049/jimmunol.179.8.5228. J Immunol. 2007. PMID: 17911608

7

New roles for TIM family members in immune regulation.

Kuchroo VK, Dardalhon V, Xiao S, Anderson AC. Kuchroo VK, et al. Nat Rev Immunol. 2008 Aug;8(8):577-80. doi: 10.1038/nri2366. Nat Rev Immunol. 2008. PMID: 18617884 Review.

8

Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression.

Xiao S, Jin H, Korn T, Liu SM, Oukka M, Lim B, Kuchroo VK. Xiao S, et al. J Immunol. 2008 Aug 15;181(4):2277-84. doi: 10.4049/jimmunol.181.4.2277. J Immunol. 2008. PMID: 18684916 Free PMC article.

9

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.

Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. Rodriguez-Manzanet R, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11. doi: 10.1073/pnas.0910359107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368430 Free PMC article.

10

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, Burns EJ, Sherr DH, Weiner HL, Kuchroo VK. Apetoh L, et al. Nat Immunol. 2010 Sep;11(9):854-61. doi: 10.1038/ni.1912. Epub 2010 Aug 1. Nat Immunol. 2010. PMID: 20676095 Free PMC article.

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