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An antibiofilm coating of 5-aryl-2-aminoimidazole covalently attached to a titanium surface.
Peeters E, Hooyberghs G, Robijns S, De Weerdt A, Kucharíková S, Tournu H, Braem A, Čeh K, Majdič G, Španič T, Pogorevc E, Claes B, Dovgan B, Girandon L, Impellizzeri F, Erdtmann M, Krona A, Vleugels J, Fröhlich M, Garcia-Forgas J, De Brucker K, Cammue BPA, Thevissen K, Van Dijck P, Vanderleyden J, Van der Eycken E, Steenackers HP. Peeters E, et al. Among authors: kucharikova s. J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1908-1919. doi: 10.1002/jbm.b.34283. Epub 2018 Dec 13. J Biomed Mater Res B Appl Biomater. 2019. PMID: 30549192
Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.
Kucharíková S, Gerits E, De Brucker K, Braem A, Ceh K, Majdič G, Španič T, Pogorevc E, Verstraeten N, Tournu H, Delattin N, Impellizzeri F, Erdtmann M, Krona A, Lövenklev M, Knezevic M, Fröhlich M, Vleugels J, Fauvart M, de Silva WJ, Vandamme K, Garcia-Forgas J, Cammue BP, Michiels J, Van Dijck P, Thevissen K. Kucharíková S, et al. J Antimicrob Chemother. 2016 Apr;71(4):936-45. doi: 10.1093/jac/dkv437. Epub 2015 Dec 24. J Antimicrob Chemother. 2016. PMID: 26702917
Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.
Gerits E, Kucharíková S, Van Dijck P, Erdtmann M, Krona A, Lövenklev M, Fröhlich M, Dovgan B, Impellizzeri F, Braem A, Vleugels J, Robijns SC, Steenackers HP, Vanderleyden J, De Brucker K, Thevissen K, Cammue BP, Fauvart M, Verstraeten N, Michiels J. Gerits E, et al. Among authors: kucharikova s. J Orthop Res. 2016 Dec;34(12):2191-2198. doi: 10.1002/jor.23238. Epub 2016 Apr 6. J Orthop Res. 2016. PMID: 27003909 Free article.
Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.
Peeters E, Hooyberghs G, Robijns S, Waldrant K, De Weerdt A, Delattin N, Liebens V, Kucharíková S, Tournu H, Verstraeten N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Van Dijck P, Michiels J, Cammue BP, Thevissen K, Vanderleyden J, Van der Eycken E, Steenackers HP. Peeters E, et al. Among authors: kucharikova s. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6483-6497. doi: 10.1128/AAC.00035-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550355 Free PMC article.
Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo.
De Cremer K, Delattin N, De Brucker K, Peeters A, Kucharíková S, Gerits E, Verstraeten N, Michiels J, Van Dijck P, Cammue BP, Thevissen K. De Cremer K, et al. Among authors: kucharikova s. Antimicrob Agents Chemother. 2014 Dec;58(12):7606-10. doi: 10.1128/AAC.03869-14. Epub 2014 Oct 6. Antimicrob Agents Chemother. 2014. PMID: 25288093 Free PMC article.
39 results