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Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.
Shchekotikhin AE, Dezhenkova LG, Tsvetkov VB, Luzikov YN, Volodina YL, Tatarskiy VV Jr, Kalinina AA, Treshalin MI, Treshalina HM, Romanenko VI, Kaluzhny DN, Kubbutat M, Schols D, Pommier Y, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: kubbutat m. Eur J Med Chem. 2016 Apr 13;112:114-129. doi: 10.1016/j.ejmech.2016.01.050. Epub 2016 Feb 4. Eur J Med Chem. 2016. PMID: 26890118 Free PMC article.
Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles.
Danilenko VN, Simonov AY, Lakatosh SA, Kubbutat MH, Totzke F, Schächtele C, Elizarov SM, Bekker OB, Printsevskaya SS, Luzikov YN, Reznikova MI, Shtil AA, Preobrazhenskaya MN. Danilenko VN, et al. Among authors: kubbutat mh. J Med Chem. 2008 Dec 25;51(24):7731-6. doi: 10.1021/jm800758s. J Med Chem. 2008. PMID: 19053831
Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases.
Cozza G, Fortuna M, Meggio F, Sarno S, Kubbutat MHG, Totzke F, Schaechtele C, Pinna LA, Olsufyeva EN, Preobrazhenskaya MN. Cozza G, et al. Among authors: kubbutat mhg. Biochemistry (Mosc). 2018 Oct;83(10):1222-1230. doi: 10.1134/S0006297918100073. Biochemistry (Mosc). 2018. PMID: 30472959 Free PMC article.
Substituted 2-arylbenzothiazoles as kinase inhibitors: hit-to-lead optimization.
Tasler S, Müller O, Wieber T, Herz T, Pegoraro S, Saeb W, Lang M, Krauss R, Totzke F, Zirrgiebel U, Ehlert JE, Kubbutat MH, Schächtele C. Tasler S, et al. Among authors: kubbutat mh. Bioorg Med Chem. 2009 Sep 15;17(18):6728-37. doi: 10.1016/j.bmc.2009.07.047. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19692247
60 results