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New 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-N-(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation.
Tomorowicz Ł, Żołnowska B, Szafrański K, Chojnacki J, Konopiński R, Grzybowska EA, Sławiński J, Kawiak A. Tomorowicz Ł, et al. Among authors: szafranski k. Int J Mol Sci. 2022 Jun 28;23(13):7178. doi: 10.3390/ijms23137178. Int J Mol Sci. 2022. PMID: 35806186 Free PMC article.
Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure-Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-N-(1H-benzo[d]imidazol-2(3H)-ylidene)Benzenesulfonamides.
Tomorowicz Ł, Sławiński J, Żołnowska B, Szafrański K, Kawiak A. Tomorowicz Ł, et al. Among authors: szafranski k. Int J Mol Sci. 2020 Apr 22;21(8):2924. doi: 10.3390/ijms21082924. Int J Mol Sci. 2020. PMID: 32331219 Free PMC article.
Target-based drug discovery through inversion of quantitative structure-drug-property relationships and molecular simulation: CA IX-sulphonamide complexes.
Žuvela P, Liu JJ, Yi M, Pomastowski PP, Sagandykova G, Belka M, David J, Bączek T, Szafrański K, Żołnowska B, Sławiński J, Supuran CT, Wong MW, Buszewski B. Žuvela P, et al. Among authors: szafranski k. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1430-1443. doi: 10.1080/14756366.2018.1511551. J Enzyme Inhib Med Chem. 2018. PMID: 30220229 Free PMC article.
Synthesis, molecular structure, and metabolic stability of new series of N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine as potential anti-cancer agents.
Pogorzelska A, Sławiński J, Kawiak A, Żołnowska B, Chojnacki J, Stasiłojć G, Ulenberg S, Szafrański K, Bączek T. Pogorzelska A, et al. Among authors: szafranski k. Eur J Med Chem. 2018 Jul 15;155:670-680. doi: 10.1016/j.ejmech.2018.06.032. Epub 2018 Jun 13. Eur J Med Chem. 2018. PMID: 29936354
Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.
Żołnowska B, Sławiński J, Szafrański K, Angeli A, Supuran CT, Kawiak A, Wieczór M, Zielińska J, Bączek T, Bartoszewska S. Żołnowska B, et al. Among authors: szafranski k. Eur J Med Chem. 2018 Jan 1;143:1931-1941. doi: 10.1016/j.ejmech.2017.11.005. Epub 2017 Nov 4. Eur J Med Chem. 2018. PMID: 29146134
Novel 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives as potent anticancer agents - Synthesis, molecular structure, QSAR studies and metabolic stability.
Pogorzelska A, Sławiński J, Żołnowska B, Szafrański K, Kawiak A, Chojnacki J, Ulenberg S, Zielińska J, Bączek T. Pogorzelska A, et al. Among authors: szafranski k. Eur J Med Chem. 2017 Sep 29;138:357-370. doi: 10.1016/j.ejmech.2017.06.059. Epub 2017 Jun 29. Eur J Med Chem. 2017. PMID: 28688276
18 results