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Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, Gether U, Byrne B, Kobilka B, Gellman SH. Chae PS, et al. Among authors: kruse ac. Nat Methods. 2010 Dec;7(12):1003-8. doi: 10.1038/nmeth.1526. Epub 2010 Oct 31. Nat Methods. 2010. PMID: 21037590 Free PMC article.
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Rasmussen SG, et al. Among authors: kruse ac. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. Nature. 2011. PMID: 21772288 Free PMC article.
Structure of the δ-opioid receptor bound to naltrindole.
Granier S, Manglik A, Kruse AC, Kobilka TS, Thian FS, Weis WI, Kobilka BK. Granier S, et al. Among authors: kruse ac. Nature. 2012 May 16;485(7398):400-4. doi: 10.1038/nature11111. Nature. 2012. PMID: 22596164 Free PMC article.
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ. Shukla AK, et al. Among authors: kruse ac. Nature. 2013 May 2;497(7447):137-41. doi: 10.1038/nature12120. Epub 2013 Apr 21. Nature. 2013. PMID: 23604254 Free PMC article.
Applications of molecular replacement to G protein-coupled receptors.
Kruse AC, Manglik A, Kobilka BK, Weis WI. Kruse AC, et al. Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2287-92. doi: 10.1107/S090744491301322X. Epub 2013 Oct 18. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 24189241 Free PMC article.
Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, Garcia KC, Wess J, Kobilka BK. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6. doi: 10.1038/nature12735. Epub 2013 Nov 20. Nature. 2013. PMID: 24256733 Free PMC article.
Covalent agonists for studying G protein-coupled receptor activation.
Weichert D, Kruse AC, Manglik A, Hiller C, Zhang C, Hübner H, Kobilka BK, Gmeiner P. Weichert D, et al. Among authors: kruse ac. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10744-8. doi: 10.1073/pnas.1410415111. Epub 2014 Jul 8. Proc Natl Acad Sci U S A. 2014. PMID: 25006259 Free PMC article.
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