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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.
Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, Grasberger H, Kao JY, Fuhrer T, Li H, Paik D, Lee Y, Refetoff S, Glickman JN, Paton AW, Bry L, Paton JC, Sauer U, Macpherson AJ, Rosenstiel P, Kuchroo VK, Waldor MK, Huh JR, Kaser A, Blumberg RS. Duan J, et al. Among authors: krupka n. Immunity. 2023 May 9;56(5):1115-1131.e9. doi: 10.1016/j.immuni.2023.02.018. Epub 2023 Mar 13. Immunity. 2023. PMID: 36917985 Free PMC article.
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.
Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute JD, Flak MB, Martinez-Naves E, Gomez Del Moral M, Glickman JN, Ohira M, Lanier LL, Kaser A, Blumberg R. Hosomi S, et al. Among authors: krupka n. J Exp Med. 2017 Oct 2;214(10):2985-2997. doi: 10.1084/jem.20162041. Epub 2017 Jul 26. J Exp Med. 2017. PMID: 28747426 Free PMC article.
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.
Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS. Grootjans J, et al. Among authors: krupka n. Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186. Science. 2019. PMID: 30819965 Free PMC article.
Progressive malnutrition despite percutaneous endoscopic gastrostomy.
Bravo F, Kapoglou I, Bionda M, Macpherson AJ, Krupka N. Bravo F, et al. Among authors: krupka n. Frontline Gastroenterol. 2020 Mar 13;12(6):535-536. doi: 10.1136/flgastro-2020-101413. eCollection 2021. Frontline Gastroenterol. 2020. PMID: 34712472 Free PMC article. No abstract available.
Plasticity of the adult human small intestinal stoma microbiota.
Yilmaz B, Fuhrer T, Morgenthaler D, Krupka N, Wang D, Spari D, Candinas D, Misselwitz B, Beldi G, Sauer U, Macpherson AJ. Yilmaz B, et al. Among authors: krupka n. Cell Host Microbe. 2022 Dec 14;30(12):1773-1787.e6. doi: 10.1016/j.chom.2022.10.002. Epub 2022 Oct 31. Cell Host Microbe. 2022. PMID: 36318918 Free article.
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Matute JD, Duan J, Flak MB, Griebel P, Tascon-Arcila JA, Doms S, Hanley T, Antanaviciute A, Gundrum J, Mark Welch JL, Sit B, Abtahi S, Fuhler GM, Grootjans J, Tran F, Stengel ST, White JR, Krupka N, Haller D, Clare S, Lawley TD, Kaser A, Simmons A, Glickman JN, Bry L, Rosenstiel P, Borisy G, Waldor MK, Baines JF, Turner JR, Blumberg RS. Matute JD, et al. Among authors: krupka n. J Exp Med. 2023 Jan 2;220(1):e20211938. doi: 10.1084/jem.20211938. Epub 2022 Nov 22. J Exp Med. 2023. PMID: 36413219 Free PMC article.
The personality traits activity, self-reproach, and negative affect jointly predict clinical recurrence, depressive symptoms, and low quality of life in inflammatory bowel disease patients.
Jordi SBU, Lang BM, Wyss J, Auschra B, Yilmaz B, Krupka N, Greuter T, Schreiner P, Biedermann L, Preisig M, von Känel R, Rogler G, Begré S, Misselwitz B; Swiss IBD cohort study group. Jordi SBU, et al. Among authors: krupka n. J Gastroenterol. 2022 Nov;57(11):848-866. doi: 10.1007/s00535-022-01902-7. Epub 2022 Jul 28. J Gastroenterol. 2022. PMID: 35900592 Free PMC article.
The oxysterol receptor GPR183 in inflammatory bowel diseases.
Misselwitz B, Wyss A, Raselli T, Cerovic V, Sailer AW, Krupka N, Ruiz F, Pot C, Pabst O. Misselwitz B, et al. Among authors: krupka n. Br J Pharmacol. 2021 Aug;178(16):3140-3156. doi: 10.1111/bph.15311. Epub 2021 Jan 12. Br J Pharmacol. 2021. PMID: 33145756 Free article. Review.
Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management.
Ledergerber M, Lang BM, Heinrich H, Biedermann L, Begré S, Zeitz J, Krupka N, Rickenbacher A, Turina M, Greuter T, Schreiner P, Roth R, Siebenhüner A, Vavricka SR, Rogler G, Beerenwinkel N, Misselwitz B; Swiss IBD Cohort Study Group. Ledergerber M, et al. Among authors: krupka n. BMC Gastroenterol. 2021 Feb 5;21(1):53. doi: 10.1186/s12876-021-01622-x. BMC Gastroenterol. 2021. PMID: 33546600 Free PMC article.
25 results