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Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin.
Vugmeyster Y, Kikuchi T, Lowes MA, Chamian F, Kagen M, Gilleaudeau P, Lee E, Howell K, Bodary S, Dummer W, Krueger JG. Vugmeyster Y, et al. Among authors: krueger jg. Clin Immunol. 2004 Oct;113(1):38-46. doi: 10.1016/j.clim.2004.06.001. Clin Immunol. 2004. PMID: 15380528
Current concepts in the immunopathogenesis of psoriasis.
Lowes MA, Lew W, Krueger JG. Lowes MA, et al. Among authors: krueger jg. Dermatol Clin. 2004 Oct;22(4):349-69, vii. doi: 10.1016/j.det.2004.03.010. Dermatol Clin. 2004. PMID: 15450332 Review.
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Chamian F, et al. Among authors: krueger jg. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2075-80. doi: 10.1073/pnas.0409569102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671179 Free PMC article. Clinical Trial.
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, Krueger JG. Lowes MA, et al. Among authors: krueger jg. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19057-62. doi: 10.1073/pnas.0509736102. Proc Natl Acad Sci U S A. 2005. PMID: 16380428 Free PMC article.
Pathogenesis and therapy of psoriasis.
Lowes MA, Bowcock AM, Krueger JG. Lowes MA, et al. Among authors: krueger jg. Nature. 2007 Feb 22;445(7130):866-73. doi: 10.1038/nature05663. Nature. 2007. PMID: 17314973 Review.
455 results