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Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform.
Arndt T, Jaudzems K, Shilkova O, Francis J, Johansson M, Laity PR, Sahin C, Chatterjee U, Kronqvist N, Barajas-Ledesma E, Kumar R, Chen G, Strömberg R, Abelein A, Langton M, Landreh M, Barth A, Holland C, Johansson J, Rising A. Arndt T, et al. Among authors: kronqvist n. Nat Commun. 2022 Aug 15;13(1):4695. doi: 10.1038/s41467-022-32093-7. Nat Commun. 2022. PMID: 35970823 Free PMC article.
Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains.
Andersson M, Chen G, Otikovs M, Landreh M, Nordling K, Kronqvist N, Westermark P, Jörnvall H, Knight S, Ridderstråle Y, Holm L, Meng Q, Jaudzems K, Chesler M, Johansson J, Rising A. Andersson M, et al. Among authors: kronqvist n. PLoS Biol. 2014 Aug 5;12(8):e1001921. doi: 10.1371/journal.pbio.1001921. eCollection 2014 Aug. PLoS Biol. 2014. PMID: 25093327 Free PMC article.
Efficient protein production inspired by how spiders make silk.
Kronqvist N, Sarr M, Lindqvist A, Nordling K, Otikovs M, Venturi L, Pioselli B, Purhonen P, Landreh M, Biverstål H, Toleikis Z, Sjöberg L, Robinson CV, Pelizzi N, Jörnvall H, Hebert H, Jaudzems K, Curstedt T, Rising A, Johansson J. Kronqvist N, et al. Nat Commun. 2017 May 23;8:15504. doi: 10.1038/ncomms15504. Nat Commun. 2017. PMID: 28534479 Free PMC article.
Mass Spectrometry Reveals the Direct Action of a Chemical Chaperone.
Gault J, Lianoudaki D, Kaldmäe M, Kronqvist N, Rising A, Johansson J, Lohkamp B, Laín S, Allison TM, Lane DP, Marklund EG, Landreh M. Gault J, et al. Among authors: kronqvist n. J Phys Chem Lett. 2018 Jul 19;9(14):4082-4086. doi: 10.1021/acs.jpclett.8b01817. Epub 2018 Jul 9. J Phys Chem Lett. 2018. PMID: 29975538 Free article.
High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry.
Kaldmäe M, Leppert A, Chen G, Sarr M, Sahin C, Nordling K, Kronqvist N, Gonzalvo-Ulla M, Fritz N, Abelein A, Laίn S, Biverstål H, Jörnvall H, Lane DP, Rising A, Johansson J, Landreh M. Kaldmäe M, et al. Among authors: kronqvist n. FEBS J. 2020 Jul;287(13):2823-2833. doi: 10.1111/febs.15169. Epub 2019 Dec 20. FEBS J. 2020. PMID: 31815338 Free PMC article.
30 results