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NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling.
Zhang T, He X, Caldwell L, Goru SK, Ulloa Severino L, Tolosa MF, Misra PS, McEvoy CM, Christova T, Liu Y, Atin C, Zhang J, Hu C, Vukosa N, Chen X, Krizova A, Kirpalani A, Gregorieff A, Ni R, Chan K, Gill MK, Attisano L, Wrana JL, Yuen DA. Zhang T, et al. Among authors: krizova a. Sci Transl Med. 2022 Mar 23;14(637):eaaz4028. doi: 10.1126/scitranslmed.aaz4028. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320001
Magnetic Resonance Elastography to Assess Fibrosis in Kidney Allografts.
Kirpalani A, Hashim E, Leung G, Kim JK, Krizova A, Jothy S, Deeb M, Jiang NN, Glick L, Mnatzakanian G, Yuen DA. Kirpalani A, et al. Among authors: krizova a. Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1671-1679. doi: 10.2215/CJN.01830217. Epub 2017 Aug 30. Clin J Am Soc Nephrol. 2017. PMID: 28855238 Free PMC article.
Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.
He X, Tolosa MF, Zhang T, Goru SK, Ulloa Severino L, Misra PS, McEvoy CM, Caldwell L, Szeto SG, Gao F, Chen X, Atin C, Ki V, Vukosa N, Hu C, Zhang J, Yip C, Krizova A, Wrana JL, Yuen DA. He X, et al. Among authors: krizova a. JCI Insight. 2022 Feb 22;7(4):e146243. doi: 10.1172/jci.insight.146243. JCI Insight. 2022. PMID: 35191398 Free PMC article.
55 results