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Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer.
Gibori H, Eliyahu S, Krivitsky A, Ben-Shushan D, Epshtein Y, Tiram G, Blau R, Ofek P, Lee JS, Ruppin E, Landsman L, Barshack I, Golan T, Merquiol E, Blum G, Satchi-Fainaro R. Gibori H, et al. Among authors: krivitsky a. Nat Commun. 2018 Jan 2;9(1):16. doi: 10.1038/s41467-017-02283-9. Nat Commun. 2018. PMID: 29295989 Free PMC article.
Identification of Dormancy-Associated MicroRNAs for the Design of Osteosarcoma-Targeted Dendritic Polyglycerol Nanopolyplexes.
Tiram G, Segal E, Krivitsky A, Shreberk-Hassidim R, Ferber S, Ofek P, Udagawa T, Edry L, Shomron N, Roniger M, Kerem B, Shaked Y, Aviel-Ronen S, Barshack I, Calderón M, Haag R, Satchi-Fainaro R. Tiram G, et al. Among authors: krivitsky a. ACS Nano. 2016 Feb 23;10(2):2028-45. doi: 10.1021/acsnano.5b06189. Epub 2016 Feb 8. ACS Nano. 2016. PMID: 26815014
Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy.
Shatsberg Z, Zhang X, Ofek P, Malhotra S, Krivitsky A, Scomparin A, Tiram G, Calderón M, Haag R, Satchi-Fainaro R. Shatsberg Z, et al. Among authors: krivitsky a. J Control Release. 2016 Oct 10;239:159-68. doi: 10.1016/j.jconrel.2016.08.029. Epub 2016 Aug 26. J Control Release. 2016. PMID: 27569663
Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome.
Ferber S, Tiram G, Sousa-Herves A, Eldar-Boock A, Krivitsky A, Scomparin A, Yeini E, Ofek P, Ben-Shushan D, Vossen LI, Licha K, Grossman R, Ram Z, Henkin J, Ruppin E, Auslander N, Haag R, Calderón M, Satchi-Fainaro R. Ferber S, et al. Among authors: krivitsky a. Elife. 2017 Oct 4;6:e25281. doi: 10.7554/eLife.25281. Elife. 2017. PMID: 28976305 Free PMC article.
Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.
Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R. Tiram G, et al. Among authors: krivitsky a. FASEB J. 2018 Jun 1:fj201701568R. doi: 10.1096/fj.201701568R. Online ahead of print. FASEB J. 2018. PMID: 29856660
EGFR up-regulation was reversed using EGFR small interfering RNA polyplex, antibody, or small-molecule inhibitor. The diminished function of TSP-1 was augmented via a peptidomimetic. The combination of EGFR inhibition and TSP-1 restoration led to enhanced therapeutic effic …
EGFR up-regulation was reversed using EGFR small interfering RNA polyplex, antibody, or small-molecule inhibitor. The diminished function of …
27 results