Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.
Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R.
Tiram G, et al. Among authors: krivitsky a.
FASEB J. 2018 Jun 1:fj201701568R. doi: 10.1096/fj.201701568R. Online ahead of print.
FASEB J. 2018.
PMID: 29856660
EGFR up-regulation was reversed using EGFR small interfering RNA polyplex, antibody, or small-molecule inhibitor. The diminished function of TSP-1 was augmented via a peptidomimetic. The combination of EGFR inhibition and TSP-1 restoration led to enhanced therapeutic effic …
EGFR up-regulation was reversed using EGFR small interfering RNA polyplex, antibody, or small-molecule inhibitor. The diminished function of …