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Design and Synthesis of Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors - In vitro Evaluation of their Antiproliferative Activity.
Batsi Y, Antonopoulou G, Fotopoulou T, Koumaki K, Kritsi E, Potamitis C, Goulielmaki M, Skarmalioraki S, Papalouka C, Poulou-Sidiropoulou E, Kosmidou V, Douna S, Vidali MS, Gkotsi EF, Chatziioannou A, Souliotis VL, Pletsa V, Papadodima O, Zoumpourlis V, Georgiadis P, Zervou M, Pintzas A, Kostas ID. Batsi Y, et al. Among authors: kritsi e. ChemMedChem. 2023 Nov 16;18(22):e202300322. doi: 10.1002/cmdc.202300322. Epub 2023 Oct 24. ChemMedChem. 2023. PMID: 37792577
BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: kritsi e. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.
Nitrate Esters of Heteroaromatic Compounds as Candida albicans CYP51 Enzyme Inhibitors.
Smiljkovic M, Matsoukas MT, Kritsi E, Zelenko U, Grdadolnik SG, Calhelha RC, Ferreira ICFR, Sankovic-Babic S, Glamoclija J, Fotopoulou T, Koufaki M, Zoumpoulakis P, Sokovic M. Smiljkovic M, et al. Among authors: kritsi e. ChemMedChem. 2018 Feb 6;13(3):251-258. doi: 10.1002/cmdc.201700602. Epub 2018 Jan 26. ChemMedChem. 2018. PMID: 29235267
Design, Synthesis, and in vitro Evaluation of P2X7 Antagonists.
T Pournara D, Durner A, Kritsi E, Papakostas A, Zoumpoulakis P, Nicke A, Koufaki M. T Pournara D, et al. Among authors: kritsi e. ChemMedChem. 2020 Dec 15;15(24):2530-2543. doi: 10.1002/cmdc.202000303. Epub 2020 Oct 16. ChemMedChem. 2020. PMID: 32964578
Exploring new scaffolds for angiotensin II receptor antagonism.
Kritsi E, Matsoukas MT, Potamitis C, Karageorgos V, Detsi A, Magafa V, Liapakis G, Mavromoustakos T, Zoumpoulakis P. Kritsi E, et al. Bioorg Med Chem. 2016 Sep 15;24(18):4444-4451. doi: 10.1016/j.bmc.2016.07.047. Epub 2016 Jul 22. Bioorg Med Chem. 2016. PMID: 27480029
28 results