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The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer.
Danielsson J, Liljedahl L, Bárány-Wallje E, Sønderby P, Kristensen LH, Martinez-Yamout MA, Dyson HJ, Wright PE, Poulsen FM, Mäler L, Gräslund A, Kragelund BB. Danielsson J, et al. Among authors: kristensen lh. Biochemistry. 2008 Dec 16;47(50):13428-37. doi: 10.1021/bi801040b. Biochemistry. 2008. PMID: 19086274 Free PMC article.
Structure and binding properties of a cameloid nanobody raised against KDM5B.
Wiuf A, Kristensen LH, Kristensen O, Dorosz J, Jensen J, Gajhede M. Wiuf A, et al. Among authors: kristensen o, kristensen lh. Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1235-41. doi: 10.1107/S2053230X1501537X. Epub 2015 Sep 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26457512 Free PMC article.
Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: towards understanding selectivity of inhibitors targeting oncogenic histone demethylases.
Kristensen JB, Nielsen AL, Jørgensen L, Kristensen LH, Helgstrand C, Juknaite L, Kristensen JL, Kastrup JS, Clausen RP, Olsen L, Gajhede M. Kristensen JB, et al. Among authors: kristensen jl, kristensen lh. FEBS Lett. 2011 Jun 23;585(12):1951-6. doi: 10.1016/j.febslet.2011.05.023. Epub 2011 May 12. FEBS Lett. 2011. PMID: 21575637 Free article.
Molecular architecture of the Jumonji C family histone demethylase KDM5B.
Dorosz J, Kristensen LH, Aduri NG, Mirza O, Lousen R, Bucciarelli S, Mehta V, Sellés-Baiget S, Solbak SMØ, Bach A, Mesa P, Hernandez PA, Montoya G, Nguyen TTTN, Rand KD, Boesen T, Gajhede M. Dorosz J, et al. Among authors: kristensen lh. Sci Rep. 2019 Mar 11;9(1):4019. doi: 10.1038/s41598-019-40573-y. Sci Rep. 2019. PMID: 30858420 Free PMC article.
Inhibitors of histone demethylases.
Lohse B, Kristensen JL, Kristensen LH, Agger K, Helin K, Gajhede M, Clausen RP. Lohse B, et al. Among authors: kristensen jl, kristensen lh. Bioorg Med Chem. 2011 Jun 15;19(12):3625-36. doi: 10.1016/j.bmc.2011.01.046. Epub 2011 Feb 1. Bioorg Med Chem. 2011. PMID: 21596573 Review.
Identification of catechols as histone-lysine demethylase inhibitors.
Nielsen AL, Kristensen LH, Stephansen KB, Kristensen JB, Helgstrand C, Lees M, Cloos P, Helin K, Gajhede M, Olsen L. Nielsen AL, et al. Among authors: kristensen jb, kristensen lh. FEBS Lett. 2012 Apr 24;586(8):1190-4. doi: 10.1016/j.febslet.2012.03.001. Epub 2012 Mar 15. FEBS Lett. 2012. PMID: 22575654 Free article.
52 results