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CD19-CD28: An affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.
Sam J, Hofer T, Kuettel C, Claus C, Thom J, Herter S, Georges G, Korfi K, Lechmann M, Eigenmann MJ, Marbach D, Jamois C, Lechner K, Krishnan SM, Gaillard BC, Marinho J, Kronenberg S, Kunz L, Wilson S, Briner S, Gebhardt S, Varol A, Appelt B, Nicolini VG, Speziale D, Bez M, Bommer E, Eckmann J, Hage C, Limani F, Jenni S, Schoenle A, Le Clech M, Vallier JB, Colombetti S, Bacac M, Gasser S, Klein C, Umaña P. Sam J, et al. Among authors: krishnan sm. Blood. 2024 Mar 4:blood.2023023381. doi: 10.1182/blood.2023023381. Online ahead of print. Blood. 2024. PMID: 38437725 Free article.
A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer.
Liu H, Milenković-Grišić AM, Krishnan SM, Jönsson S, Friberg LE, Girard P, Venkatakrishnan K, Vugmeyster Y, Khandelwal A, Karlsson MO. Liu H, et al. Among authors: krishnan sm. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1738-1750. doi: 10.1002/psp4.12976. Epub 2023 May 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37165943 Free PMC article.
Bayesian forecasting of tumor size metrics and overall survival.
Krishnan SM, Friberg LE. Krishnan SM, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1604-1613. doi: 10.1002/psp4.12869. Epub 2022 Oct 4. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36194478 Free PMC article.
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial.
Gurevich I, Agarwal P, Zhang P, Dolorito JA, Oliver S, Liu H, Reitze N, Sarma N, Bagci IS, Sridhar K, Kakarla V, Yenamandra VK, O'Malley M, Prisco M, Tufa SF, Keene DR, South AP, Krishnan SM, Marinkovich MP. Gurevich I, et al. Among authors: krishnan sm. Nat Med. 2022 Apr;28(4):780-788. doi: 10.1038/s41591-022-01737-y. Epub 2022 Mar 28. Nat Med. 2022. PMID: 35347281 Free PMC article. Clinical Trial.
72 results