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A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. Jang C, et al. Among authors: krishnaiah s. Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7. Nat Med. 2016. PMID: 26950361 Free PMC article.
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.
Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM. Krishnaiah SY, et al. Cell Metab. 2017 Apr 4;25(4):961-974.e4. doi: 10.1016/j.cmet.2017.03.019. Cell Metab. 2017. PMID: 28380384 Free PMC article.
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.
Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM. Krishnaiah SY, et al. Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.023. Cell Metab. 2017. PMID: 28467936 Free article. No abstract available.
p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2).
Krishnaiah SY, Dodia C, Feinstein SI, Fisher AB. Krishnaiah SY, et al. FASEB J. 2013 May;27(5):2066-73. doi: 10.1096/fj.12-222133. Epub 2013 Feb 11. FASEB J. 2013. PMID: 23401562 Free PMC article.
These data indicate that p67(phox) binds to phosphoPrdx6 and inhibits its PLA2 activity, an interaction that could function to terminate the PLA2-mediated NOX2 activation signal.-Krishnaiah, S. Y., Dodia, C., Feinstein, S. I., and Fisher, A. B. p67(phox) term …
These data indicate that p67(phox) binds to phosphoPrdx6 and inhibits its PLA2 activity, an interaction that could function to terminate the …
Plasma metabolite profiling identifies non-diabetic CP patients with metabolic alterations progressing to prediabetes prior to HbA1c.
Vijayasarathy K, Ramunaidu A, Ragi N, Pavankumar P, Simhadri V, Manne S, Krishnaiah S, Aslam M, Talukadar R, Devi CV, Rao GV, Amanchy R, Reddy DN, Sripadi P, Sasikala M. Vijayasarathy K, et al. Among authors: krishnaiah s. Clin Transl Gastroenterol. 2024 Apr 25. doi: 10.14309/ctg.0000000000000704. Online ahead of print. Clin Transl Gastroenterol. 2024. PMID: 38661171
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