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Page 1
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties.
Sela T, Mansø M, Siegel M, Marban-Doran C, Ducret A, Niewöhner J, Ravn J, Martin RE, Sommer A, Lohmann S, Krippendorff BF, Ladefoged M, Indlekofer A, Quaiser T, Bueddefeld F, Koller E, Mohamed MY, Oelschlaegel T, Gothelf KV, Hofer K, Schumacher FF. Sela T, et al. Among authors: krippendorff bf. Bioconjug Chem. 2023 Nov 15;34(11):2096-2111. doi: 10.1021/acs.bioconjchem.3c00393. Epub 2023 Nov 2. Bioconjug Chem. 2023. PMID: 37916986
Translating pharmacology models effectively to predict therapeutic benefit.
Dudal S, Bissantz C, Caruso A, David-Pierson P, Driessen W, Koller E, Krippendorff BF, Lechmann M, Olivares-Morales A, Paehler A, Rynn C, Türck D, Van De Vyver A, Wang K, Winther L. Dudal S, et al. Among authors: krippendorff bf. Drug Discov Today. 2022 Jun;27(6):1604-1621. doi: 10.1016/j.drudis.2022.03.009. Epub 2022 Mar 15. Drug Discov Today. 2022. PMID: 35304340 Free article. Review.
Reply.
Wat C, Gane E, Yuen MF, Pavlovic V, Mueller H, Krippendorff BF, Grippo JF, Ottosen S. Wat C, et al. Among authors: krippendorff bf. Hepatology. 2022 Apr;75(4):1050-1051. doi: 10.1002/hep.32113. Epub 2021 Dec 13. Hepatology. 2022. PMID: 34396570 No abstract available.
Clinical Study of Single-Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B.
Gane E, Yuen MF, Kim DJ, Chan HL, Surujbally B, Pavlovic V, Das S, Triyatni M, Kazma R, Grippo JF, Buatois S, Lemenuel-Diot A, Krippendorff BF, Mueller H, Zhang Y, Kim HJ, Leerapun A, Lim TH, Lim YS, Tanwandee T, Kim W, Cheng W, Hu TH, Wat C. Gane E, et al. Among authors: krippendorff bf. Hepatology. 2021 Oct;74(4):1795-1808. doi: 10.1002/hep.31920. Epub 2021 Aug 25. Hepatology. 2021. PMID: 34037271 Free PMC article. Clinical Trial.
A re-engineered immunotoxin shows promising preclinical activity in ovarian cancer.
Kollmorgen G, Palme K, Seidl A, Scheiblich S, Birzele F, Wilson S, Clemens C, Voss E, Kaufmann M, Hirzel K, Rieder N, Krippendorff BF, Herting F, Niederfellner G. Kollmorgen G, et al. Among authors: krippendorff bf. Sci Rep. 2017 Dec 22;7(1):18086. doi: 10.1038/s41598-017-17329-7. Sci Rep. 2017. PMID: 29273809 Free PMC article.
Quantification of IgG monoclonal antibody clearance in tissues.
Eigenmann MJ, Fronton L, Grimm HP, Otteneder MB, Krippendorff BF. Eigenmann MJ, et al. Among authors: krippendorff bf. MAbs. 2017 Aug/Sep;9(6):1007-1015. doi: 10.1080/19420862.2017.1337619. Epub 2017 Jun 14. MAbs. 2017. PMID: 28613103 Free PMC article.
Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy.
Bauss F, Lechmann M, Krippendorff BF, Staack R, Herting F, Festag M, Imhof-Jung S, Hesse F, Pompiati M, Kollmorgen G, da Silva Mateus Seidl R, Bossenmaier B, Lau W, Schantz C, Stracke JO, Brinkmann U, Onda M, Pastan I, Bosslet K, Niederfellner G. Bauss F, et al. Among authors: krippendorff bf. Mol Oncol. 2016 Oct;10(8):1317-29. doi: 10.1016/j.molonc.2016.07.003. Epub 2016 Jul 14. Mol Oncol. 2016. PMID: 27507537 Free PMC article.
19 results