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Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus.
Greiling TM, Dehner C, Chen X, Hughes K, Iñiguez AJ, Boccitto M, Ruiz DZ, Renfroe SC, Vieira SM, Ruff WE, Sim S, Kriegel C, Glanternik J, Chen X, Girardi M, Degnan P, Costenbader KH, Goodman AL, Wolin SL, Kriegel MA. Greiling TM, et al. Among authors: kriegel c. Sci Transl Med. 2018 Mar 28;10(434):eaan2306. doi: 10.1126/scitranslmed.aan2306. Sci Transl Med. 2018. PMID: 29593104 Free PMC article.
Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity.
Ruff WE, Dehner C, Kim WJ, Pagovich O, Aguiar CL, Yu AT, Roth AS, Vieira SM, Kriegel C, Adeniyi O, Mulla MJ, Abrahams VM, Kwok WW, Nussinov R, Erkan D, Goodman AL, Kriegel MA. Ruff WE, et al. Among authors: kriegel c. Cell Host Microbe. 2019 Jul 10;26(1):100-113.e8. doi: 10.1016/j.chom.2019.05.003. Epub 2019 Jun 18. Cell Host Microbe. 2019. PMID: 31227334 Free PMC article.
Translocation of a gut pathobiont drives autoimmunity in mice and humans.
Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Manfredo Vieira S, et al. Among authors: kriegel c. Science. 2018 Mar 9;359(6380):1156-1161. doi: 10.1126/science.aar7201. Science. 2018. PMID: 29590047 Free PMC article.
Modelling of a targeted nanotherapeutic 'stroma' to deliver the cytokine LIF, or XAV939, a potent inhibitor of Wnt-β-catenin signalling, for use in human fetal dopaminergic grafts in Parkinson's disease.
Zhao JW, Dyson SC, Kriegel C, Tyers P, He X, Fahmy TM, Metcalfe SM, Barker RA. Zhao JW, et al. Among authors: kriegel c. Dis Model Mech. 2014 Oct;7(10):1193-203. doi: 10.1242/dmm.015859. Epub 2014 Aug 1. Dis Model Mech. 2014. PMID: 25085990 Free PMC article.
Delivery strategies to enhance mucosal vaccination.
Chadwick S, Kriegel C, Amiji M. Chadwick S, et al. Among authors: kriegel c. Expert Opin Biol Ther. 2009 Apr;9(4):427-40. doi: 10.1517/14712590902849224. Expert Opin Biol Ther. 2009. PMID: 19344280 Review.
Nanotechnology solutions for mucosal immunization.
Chadwick S, Kriegel C, Amiji M. Chadwick S, et al. Among authors: kriegel c. Adv Drug Deliv Rev. 2010 Mar 18;62(4-5):394-407. doi: 10.1016/j.addr.2009.11.012. Epub 2009 Nov 18. Adv Drug Deliv Rev. 2010. PMID: 19931581 Review.
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