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Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Fischer K, Hoffmann P, Voelkl S, Meidenbauer N, Ammer J, Edinger M, Gottfried E, Schwarz S, Rothe G, Hoves S, Renner K, Timischl B, Mackensen A, Kunz-Schughart L, Andreesen R, Krause SW, Kreutz M. Fischer K, et al. Among authors: kreutz m. Blood. 2007 May 1;109(9):3812-9. doi: 10.1182/blood-2006-07-035972. Epub 2007 Jan 25. Blood. 2007. PMID: 17255361 Free article. Clinical Trial.
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Dietl K, Renner K, Dettmer K, Timischl B, Eberhart K, Dorn C, Hellerbrand C, Kastenberger M, Kunz-Schughart LA, Oefner PJ, Andreesen R, Gottfried E, Kreutz MP. Dietl K, et al. Among authors: kreutz mp. J Immunol. 2010 Feb 1;184(3):1200-9. doi: 10.4049/jimmunol.0902584. Epub 2009 Dec 21. J Immunol. 2010. PMID: 20026743
Warburg phenotype in renal cell carcinoma: high expression of glucose-transporter 1 (GLUT-1) correlates with low CD8(+) T-cell infiltration in the tumor.
Singer K, Kastenberger M, Gottfried E, Hammerschmied CG, Büttner M, Aigner M, Seliger B, Walter B, Schlösser H, Hartmann A, Andreesen R, Mackensen A, Kreutz M. Singer K, et al. Among authors: kreutz m. Int J Cancer. 2011 May 1;128(9):2085-95. doi: 10.1002/ijc.25543. Int J Cancer. 2011. PMID: 20607826 Free article.
Suppression of T-cell responses by tumor metabolites.
Singer K, Gottfried E, Kreutz M, Mackensen A. Singer K, et al. Among authors: kreutz m. Cancer Immunol Immunother. 2011 Mar;60(3):425-31. doi: 10.1007/s00262-010-0967-1. Epub 2011 Jan 15. Cancer Immunol Immunother. 2011. PMID: 21240484 Free PMC article. Review.
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
Gottfried E, Lang SA, Renner K, Bosserhoff A, Gronwald W, Rehli M, Einhell S, Gedig I, Singer K, Seilbeck A, Mackensen A, Grauer O, Hau P, Dettmer K, Andreesen R, Oefner PJ, Kreutz M. Gottfried E, et al. Among authors: kreutz m. PLoS One. 2013 Jul 9;8(7):e66987. doi: 10.1371/journal.pone.0066987. Print 2013. PLoS One. 2013. PMID: 23874405 Free PMC article.
Transcription and enhancer profiling in human monocyte subsets.
Schmidl C, Renner K, Peter K, Eder R, Lassmann T, Balwierz PJ, Itoh M, Nagao-Sato S, Kawaji H, Carninci P, Suzuki H, Hayashizaki Y, Andreesen R, Hume DA, Hoffmann P, Forrest AR, Kreutz MP, Edinger M, Rehli M; FANTOM consortium. Schmidl C, et al. Among authors: kreutz mp. Blood. 2014 Apr 24;123(17):e90-9. doi: 10.1182/blood-2013-02-484188. Epub 2014 Mar 26. Blood. 2014. PMID: 24671955 Free article.
Lactic acid delays the inflammatory response of human monocytes.
Peter K, Rehli M, Singer K, Renner-Sattler K, Kreutz M. Peter K, et al. Among authors: kreutz m. Biochem Biophys Res Commun. 2015 Feb 13;457(3):412-8. doi: 10.1016/j.bbrc.2015.01.005. Epub 2015 Jan 9. Biochem Biophys Res Commun. 2015. PMID: 25582773
349 results