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Human organoids are superior to cell culture models for intestinal barrier research.
Kollmann C, Buerkert H, Meir M, Richter K, Kretzschmar K, Flemming S, Kelm M, Germer CT, Otto C, Burkard N, Schlegel N. Kollmann C, et al. Among authors: kretzschmar k. Front Cell Dev Biol. 2023 Oct 2;11:1223032. doi: 10.3389/fcell.2023.1223032. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37849736 Free PMC article.
Chromatin Remodeling in Patient-Derived Colorectal Cancer Models.
Xiang K, Wang E, Mantyh J, Rupprecht G, Negrete M, Sanati G, Hsu C, Randon P, Dohlman A, Kretzschmar K, Bose S, Giroux N, Ding S, Wang L, Balcazar JP, Huang Q, Sundaramoorthy P, Xi R, McCall SJ, Wang Z, Jiang C, Kang Y, Kopetz S, Crawford GE, Lipkin SM, Wang XF, Clevers H, Hsu D, Shen X. Xiang K, et al. Among authors: kretzschmar k. Adv Sci (Weinh). 2024 Apr;11(16):e2303379. doi: 10.1002/advs.202303379. Epub 2024 Feb 21. Adv Sci (Weinh). 2024. PMID: 38380561 Free PMC article.
Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures.
Yang ASP, Dutta D, Kretzschmar K, Hendriks D, Puschhof J, Hu H, Boonekamp KE, van Waardenburg Y, Chuva de Sousa Lopes SM, van Gemert GJ, de Wilt JHW, Bousema T, Clevers H, Sauerwein RW. Yang ASP, et al. Among authors: kretzschmar k. Nat Commun. 2023 Aug 2;14(1):4631. doi: 10.1038/s41467-023-40298-7. Nat Commun. 2023. PMID: 37532704 Free PMC article.
Uncovering the mode of action of engineered T cells in patient cancer organoids.
Dekkers JF, Alieva M, Cleven A, Keramati F, Wezenaar AKL, van Vliet EJ, Puschhof J, Brazda P, Johanna I, Meringa AD, Rebel HG, Buchholz MB, Barrera Román M, Zeeman AL, de Blank S, Fasci D, Geurts MH, Cornel AM, Driehuis E, Millen R, Straetemans T, Nicolasen MJT, Aarts-Riemens T, Ariese HCR, Johnson HR, van Ineveld RL, Karaiskaki F, Kopper O, Bar-Ephraim YE, Kretzschmar K, Eggermont AMM, Nierkens S, Wehrens EJ, Stunnenberg HG, Clevers H, Kuball J, Sebestyen Z, Rios AC. Dekkers JF, et al. Among authors: kretzschmar k. Nat Biotechnol. 2023 Jan;41(1):60-69. doi: 10.1038/s41587-022-01397-w. Epub 2022 Jul 25. Nat Biotechnol. 2023. PMID: 35879361 Free PMC article.
Single-cell derived tumor organoids display diversity in HLA class I peptide presentation.
Demmers LC, Kretzschmar K, Van Hoeck A, Bar-Epraïm YE, van den Toorn HWP, Koomen M, van Son G, van Gorp J, Pronk A, Smakman N, Cuppen E, Clevers H, Heck AJR, Wu W. Demmers LC, et al. Among authors: kretzschmar k. Nat Commun. 2020 Oct 21;11(1):5338. doi: 10.1038/s41467-020-19142-9. Nat Commun. 2020. PMID: 33087703 Free PMC article.
102 results