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Correction: Encapsulation of the dual FLAP/mPEGS‑1 inhibitor BRP‑187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.
Shkodra B, Kretzer C, Jordan PM, Klemm P, Koeberle A, Pretzel D, Banoglu E, Lorkowski S, Wallert M, Höppener S, Stumpf S, Vollrath A, Schubert S, Werz O, Schubert US. Shkodra B, et al. Among authors: kretzer c. J Nanobiotechnology. 2024 Feb 27;22(1):77. doi: 10.1186/s12951-024-02341-7. J Nanobiotechnology. 2024. PMID: 38408973 Free PMC article. No abstract available.
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators.
Peltner LK, Gluthmann L, Börner F, Pace S, Hoffstetter RK, Kretzer C, Bilancia R, Pollastro F, Koeberle A, Appendino G, Rossi A, Newcomer ME, Gilbert NC, Werz O, Jordan PM. Peltner LK, et al. Among authors: kretzer c. Cell Chem Biol. 2023 Dec 21;30(12):1508-1524.e7. doi: 10.1016/j.chembiol.2023.08.001. Epub 2023 Aug 29. Cell Chem Biol. 2023. PMID: 37647900
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors.
Potenza M, Giordano A, Chini MG, Saviano A, Kretzer C, Raucci F, Russo M, Lauro G, Terracciano S, Bruno I, Iorizzi M, Hofstetter RK, Pace S, Maione F, Werz O, Bifulco G. Potenza M, et al. Among authors: kretzer c. ACS Med Chem Lett. 2022 Dec 9;14(1):26-34. doi: 10.1021/acsmedchemlett.2c00343. eCollection 2023 Jan 12. ACS Med Chem Lett. 2022. PMID: 36655121 Free PMC article.
Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophages.
Rao Z, Caprioglio D, Gollowitzer A, Kretzer C, Imperio D, Collado JA, Waltl L, Lackner S, Appendino G, Muñoz E, Temml V, Werz O, Minassi A, Koeberle A. Rao Z, et al. Among authors: kretzer c. Biochem Pharmacol. 2022 Sep;203:115202. doi: 10.1016/j.bcp.2022.115202. Epub 2022 Aug 3. Biochem Pharmacol. 2022. PMID: 35932797 Free article.
Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood.
Kretzer C, Shkodra B, Klemm P, Jordan PM, Schröder D, Cinar G, Vollrath A, Schubert S, Nischang I, Hoeppener S, Stumpf S, Banoglu E, Gladigau F, Bilancia R, Rossi A, Eggeling C, Neugebauer U, Schubert US, Werz O. Kretzer C, et al. Cell Mol Life Sci. 2021 Dec 31;79(1):40. doi: 10.1007/s00018-021-04039-7. Cell Mol Life Sci. 2021. PMID: 34971430 Free PMC article.
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