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Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30.
Nature. 2022.
PMID: 35355013
Free PMC article.
STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury.
Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E 3rd, Beers MF, Weitzman MD, Morrisey EE, Worthen GS.
Paris AJ, et al. Among authors: kremp mm.
Nat Cell Biol. 2020 Oct;22(10):1197-1210. doi: 10.1038/s41556-020-0569-x. Epub 2020 Sep 28.
Nat Cell Biol. 2020.
PMID: 32989251
Free PMC article.
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Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus.
Zepp JA, Morley MP, Loebel C, Kremp MM, Chaudhry FN, Basil MC, Leach JP, Liberti DC, Niethamer TK, Ying Y, Jayachandran S, Babu A, Zhou S, Frank DB, Burdick JA, Morrisey EE.
Zepp JA, et al. Among authors: kremp mm.
Science. 2021 Mar 12;371(6534):eabc3172. doi: 10.1126/science.abc3172.
Science. 2021.
PMID: 33707239
Free PMC article.
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Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration.
Penkala IJ, Liberti DC, Pankin J, Sivakumar A, Kremp MM, Jayachandran S, Katzen J, Leach JP, Windmueller R, Stolz K, Morley MP, Babu A, Zhou S, Frank DB, Morrisey EE.
Penkala IJ, et al. Among authors: kremp mm.
Cell Stem Cell. 2021 Oct 7;28(10):1775-1789.e5. doi: 10.1016/j.stem.2021.04.026. Epub 2021 May 10.
Cell Stem Cell. 2021.
PMID: 33974915
Free PMC article.
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Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury.
Liberti DC, Kremp MM, Liberti WA 3rd, Penkala IJ, Li S, Zhou S, Morrisey EE.
Liberti DC, et al. Among authors: kremp mm.
Cell Rep. 2021 May 11;35(6):109092. doi: 10.1016/j.celrep.2021.109092.
Cell Rep. 2021.
PMID: 33979629
Free PMC article.
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Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration.
Liberti DC, Liberti Iii WA, Kremp MM, Penkala IJ, Cardenas-Diaz FL, Morley MP, Babu A, Zhou S, Fernandez Iii RJ, Morrisey EE.
Liberti DC, et al. Among authors: kremp mm.
Dev Cell. 2022 Jul 25;57(14):1742-1757.e5. doi: 10.1016/j.devcel.2022.06.007. Epub 2022 Jul 7.
Dev Cell. 2022.
PMID: 35803279
Free article.
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The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting.
Dunlevy KL, Medvedeva V, Wilson JE, Hoque M, Pellegrin T, Maynard A, Kremp MM, Wasserman JS, Poleshko A, Katz RA.
Dunlevy KL, et al. Among authors: kremp mm.
J Cell Sci. 2020 May 27;133(10):jcs240416. doi: 10.1242/jcs.240416.
J Cell Sci. 2020.
PMID: 32317397
Free PMC article.
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