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High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.
Eckhardt C, Sbiera I, Krebs M, Sbiera S, Spahn M, Kneitz B, Joniau S, Fassnacht M, Kübler H, Weigand I, Kroiss M. Eckhardt C, et al. Among authors: krebs m. Prostate Cancer Prostatic Dis. 2022 Sep;25(3):484-490. doi: 10.1038/s41391-021-00431-3. Epub 2021 Jul 29. Prostate Cancer Prostatic Dis. 2022. PMID: 34326474 Free PMC article.
Survival in patients with high-risk prostate cancer is predicted by miR-221, which regulates proliferation, apoptosis, and invasion of prostate cancer cells by inhibiting IRF2 and SOCS3.
Kneitz B, Krebs M, Kalogirou C, Schubert M, Joniau S, van Poppel H, Lerut E, Kneitz S, Scholz CJ, Ströbel P, Gessler M, Riedmiller H, Spahn M. Kneitz B, et al. Among authors: krebs m. Cancer Res. 2014 May 1;74(9):2591-603. doi: 10.1158/0008-5472.CAN-13-1606. Epub 2014 Mar 7. Cancer Res. 2014. PMID: 24607843
985 results