Kranz A - Search Results

1

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.

Hanna CW, Taudt A, Huang J, Gahurova L, Kranz A, Andrews S, Dean W, Stewart AF, Colomé-Tatché M, Kelsey G. Hanna CW, et al. Among authors: kranz a. Nat Struct Mol Biol. 2018 Jan;25(1):73-82. doi: 10.1038/s41594-017-0013-5. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323282

2

Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation.

Hanna CW, Huang J, Belton C, Reinhardt S, Dahl A, Andrews S, Stewart AF, Kranz A, Kelsey G. Hanna CW, et al. Among authors: kranz a. Nucleic Acids Res. 2022 Feb 28;50(4):1993-2004. doi: 10.1093/nar/gkac051. Nucleic Acids Res. 2022. PMID: 35137160 Free PMC article.

3

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF. Denissov S, et al. Among authors: kranz a. Development. 2014 Feb;141(3):526-37. doi: 10.1242/dev.102681. Epub 2014 Jan 14. Development. 2014. PMID: 24423662

4

Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.

Brici D, Zhang Q, Reinhardt S, Dahl A, Hartmann H, Schmidt K, Goveas N, Huang J, Gahurova L, Kelsey G, Anastassiadis K, Stewart AF, Kranz A. Brici D, et al. Among authors: kranz a. Development. 2017 Jul 15;144(14):2606-2617. doi: 10.1242/dev.143347. Epub 2017 Jun 15. Development. 2017. PMID: 28619824

5

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

Bledau AS, Schmidt K, Neumann K, Hill U, Ciotta G, Gupta A, Torres DC, Fu J, Kranz A, Stewart AF, Anastassiadis K. Bledau AS, et al. Among authors: kranz a. Development. 2014 Mar;141(5):1022-35. doi: 10.1242/dev.098152. Development. 2014. PMID: 24550110

6

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.

Chen Y, Anastassiadis K, Kranz A, Stewart AF, Arndt K, Waskow C, Yokoyama A, Jones K, Neff T, Lee Y, Ernst P. Chen Y, et al. Among authors: kranz a. Cancer Cell. 2017 Jun 12;31(6):755-770.e6. doi: 10.1016/j.ccell.2017.05.002. Cancer Cell. 2017. PMID: 28609655 Free PMC article.

7

MLL1 is required for maintenance of intestinal stem cells.

Goveas N, Waskow C, Arndt K, Heuberger J, Zhang Q, Alexopoulou D, Dahl A, Birchmeier W, Anastassiadis K, Stewart AF, Kranz A. Goveas N, et al. Among authors: kranz a. PLoS Genet. 2021 Dec 3;17(12):e1009250. doi: 10.1371/journal.pgen.1009250. eCollection 2021 Dec. PLoS Genet. 2021. PMID: 34860830 Free PMC article.

8

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.

Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: kranz a. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.

9

Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.

Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P. Chen Y, et al. Among authors: kranz a. Exp Hematol. 2019 Jan;69:37-42. doi: 10.1016/j.exphem.2018.10.001. Epub 2018 Oct 10. Exp Hematol. 2019. PMID: 30315824 Free PMC article.

10

Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.

Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: kranz a. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.

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