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Pharmacological inhibition of FTO.
McMurray F, Demetriades M, Aik W, Merkestein M, Kramer H, Andrew DS, Scudamore CL, Hough TA, Wells S, Ashcroft FM, McDonough MA, Schofield CJ, Cox RD. McMurray F, et al. Among authors: kramer h. PLoS One. 2015 Apr 1;10(4):e0121829. doi: 10.1371/journal.pone.0121829. eCollection 2015. PLoS One. 2015. PMID: 25830347 Free PMC article.
Changes in gene expression associated with FTO overexpression in mice.
Merkestein M, McTaggart JS, Lee S, Kramer HB, McMurray F, Lafond M, Boutens L, Cox R, Ashcroft FM. Merkestein M, et al. PLoS One. 2014 May 19;9(5):e97162. doi: 10.1371/journal.pone.0097162. eCollection 2014. PLoS One. 2014. PMID: 24842286 Free PMC article.
Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.
Pfeffer I, Brewitz L, Krojer T, Jensen SA, Kochan GT, Kershaw NJ, Hewitson KS, McNeill LA, Kramer H, Münzel M, Hopkinson RJ, Oppermann U, Handford PA, McDonough MA, Schofield CJ. Pfeffer I, et al. Among authors: kramer h. Nat Commun. 2019 Oct 28;10(1):4910. doi: 10.1038/s41467-019-12711-7. Nat Commun. 2019. PMID: 31659163 Free PMC article.
Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation.
Scotti JS, Leung IK, Ge W, Bentley MA, Paps J, Kramer HB, Lee J, Aik W, Choi H, Paulsen SM, Bowman LA, Loik ND, Horita S, Ho CH, Kershaw NJ, Tang CM, Claridge TD, Preston GM, McDonough MA, Schofield CJ. Scotti JS, et al. Among authors: kramer hb. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13331-6. doi: 10.1073/pnas.1409916111. Epub 2014 Sep 2. Proc Natl Acad Sci U S A. 2014. PMID: 25197067 Free PMC article.
1,433 results